SCHEMBL451303

SCHEMBL451303

[c]1[c]c2[nH]ncc2cc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18771 0.70
SCHEMBL70450 0.65
SCHEMBL452320 0.65
SCHEMBL21722169 0.64 MAPT (0.40)
SCHEMBL291015 0.62
SCHEMBL23442 0.61
SCHEMBL8557222 0.59
SCHEMBL4310693 0.58 NOS1 (0.41)
SCHEMBL2595179 0.58 MAPT (0.47)
SCHEMBL23081 0.56

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4882249-A PHOTOSENSITIVITY, DURABILITY FUJI PHOTO FILM CO., LTD. (JP) 1989-11-21 US claimed
US-4871637-A DURABILITY, PHOTOSENSITIVITY FUJI PHOTO FILM CO., LTD. (JP) 1989-10-03 US claimed
US-4791194-A DURABILITY; ELECTROGRAPHY MITSUBISHI CHEMICAL INDUSTRIES, LTD. (JP) 1988-12-13 US claimed
EP-0150707-B1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR MITSUBISHI KASEI CORPORATION (JP) 1988-04-13 EP claimed
EP-0150707-A1 Electrophotographic photoreceptor MITSUBISHI KASEI CORPORATION (JP) 1985-08-07 EP claimed
US-4190661-A BACTERICIDES LABORATOIRES CHAUVIN-BLACHE (FR) 1980-02-26 US claimed
JP-57176055-A None JP disclosed
US-20150216861-A1 CYCLOPROPYL AMIDE DERIVATIVES ASTRAZENECA AB (SE) 2015-08-06 US disclosed
US-9029381-B2 Cyclopropyl amide derivatives ASTRAZENECA AB (SE) 2015-05-12 US disclosed
EP-2805937-A1 Cyclopropyl amide derivatives AstraZeneca AB (SE) 2014-11-26 EP disclosed
EP-2253615-B1 Cyclopropyl amide derivatives ASTRAZENECA AB (SE) 2014-07-09 EP disclosed
EP-2195293-B1 CYCLOPTOPYL AMIDE DERIVATIVES ASTRAZENECA AB (SE) 2013-10-16 EP disclosed
US-20120065193-A1 Cyclopropyl Amide Derivatives '978 ASTRAZENECA AB (SE) 2012-03-15 US disclosed
US-4702982-A Electrophotographic photosensitive member comprising disazo pigment CANON KABUSHIKI KAISHA (JP) 1987-10-27 US disclosed
US-4618555-A PHOTOSENSITIVITY; DURABILITY MITSUBISHI CHEMICAL IND., LTD. (JP) 1986-10-21 US disclosed
EP-0063387-B1 ELECTROPHOTOGRAPHIC PLATE MITSUBISHI KASEI CORPORATION (JP) 1986-07-23 EP disclosed
EP-0150707-A1 Electrophotographic photoreceptor MITSUBISHI KASEI CORPORATION (JP) 1985-08-07 EP disclosed
US-4396696-A Electrophotographic plate having azo compound photosensitive layer MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) 1983-08-02 US disclosed
JP-S57176055-A ELECTROPHOTOGRAPHIC RECEPTOR MITSUBISHI CHEM IND LTD 1982-10-29 JP disclosed
EP-0063387-A1 Electrophotographic plate MITSUBISHI KASEI CORPORATION (JP) 1982-10-27 EP disclosed