Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | PKM | P14618 | 3/20 | 0.47 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | FABP1 | P07148 | 1/20 | 0.44 |
| ▸ | FABP6 | P51161 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31216658 | 1.00 | KDM4E (0.50) | KDM4EMEN1KMT2AMAPK10GFER | |
| SCHEMBL28069466 | 0.78 | KDM4E (0.47) | KDM4EMEN1KMT2AMAPK10GFER | |
| SCHEMBL7448182 | 0.77 | MEN1 (0.50) | KDM4EMEN1KMT2AMAPK10GFER | |
| SCHEMBL28279163 | 0.76 | MEN1 (0.48) | KDM4EMEN1KMT2AMAPK10GFER | |
| SCHEMBL3851269 | 0.76 | MEN1 (0.48) | KDM4EMEN1KMT2AMAPK10GFER | |
| SCHEMBL19581189 | 0.76 | MEN1 (0.48) | KDM4EMEN1KMT2AMAPK10GFER | |
| SCHEMBL9376222 | 0.74 | NPC1 (0.48) | KDM4EMEN1KMT2AMAPK10GFER | |
| SCHEMBL24134532 | 0.73 | — | — | |
| SCHEMBL1274368 | 0.72 | CXCR4 (0.55) | KDM4EMEN1KMT2AMAPK10GFER | |
| SCHEMBL29552506 | 0.72 | CXCR4 (0.55) | KDM4EMEN1KMT2AMAPK10GFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023179771-A1 | CRYSTALLINE FORMS AND SALTS OF A PI3K INHIBITOR AND METHODS OF MAKING AND METHODS OF USE THEREOF | TOTUS MEDICINES INC. (US) | 2023-09-28 | — | — | WO | disclosed |
| EP-3993707-A1 | USE OF ULTRAFAST ELASTICITY IMAGING FOR DETECTING PANCREATIC CANCERS | Institut National de la Santé et de la Recherche Médicale (INSERM) (FR) | 2022-05-11 | — | — | EP | disclosed |
| WO-2021001426-A1 | USE OF ULTRAFAST ELASTICITY IMAGING FOR DETECTING PANCREATIC CANCERS | INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) | 2021-01-07 | — | — | WO | disclosed |
| US-20090258882-A1 | 2,4-Substituted Quinazolines as Lipid Kinase Inhibitors | NOVARTIS AG | 2009-10-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090258882-A1 | 2,4-Substituted Quinazolines as Lipid Kinase Inhibitors | PDPK1, PI4KA, PIK3CA | KDM4E 1674/4885MEN1 4278/4885KMT2A 1748/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.