Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | PKM | P14618 | 3/20 | 0.44 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | FABP1 | P07148 | 1/20 | 0.41 |
| ▸ | FABP6 | P51161 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10405315 | 0.79 | MEN1 (0.61) | KDM4EMEN1KMT2AMAPK10GFER | |
| SCHEMBL7194702 | 0.79 | MEN1 (0.47) | KDM4EMEN1KMT2AMAPK10GFER | |
| SCHEMBL31216658 | 0.78 | KDM4E (0.50) | KDM4EMEN1KMT2AMAPK10GFER | |
| SCHEMBL4513657 | 0.78 | KDM4E (0.50) | KDM4EMEN1KMT2AMAPK10GFER | |
| Hydrochloric Acid SCHEMBL8742967 | 0.77 | MEN1 (0.58) | KDM4EMEN1KMT2AMAPK10GFER | |
| SCHEMBL27370986 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL28166660 | 0.74 | MEN1 (0.50) | KDM4EMEN1KMT2AMAPK10GFER | |
| SCHEMBL23352486 | 0.73 | CXCR4 (0.42) | KDM4EMEN1KMT2AMAPK10GFER | |
| SCHEMBL11405577 | 0.72 | GAA (0.58) | KDM4EMEN1KMT2AGFERNPC1 | |
| SCHEMBL2227737 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105541706-A | 3-Chloro-2-hydrazino-5-trifluoromethylpyridine derivative, and preparation method and application thereof | UNIV ZHEJIANG TECHNOLOGY | 2016-05-04 | — | — | CN | disclosed |