Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 14/20 | 0.57 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | BCR | P11274 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10992866 | 0.74 | AKR1C3 (0.56) | GRM5ABL1BCRLMNA | |
| SCHEMBL990293 | 0.73 | GRM5 (0.71) | GRM5 | |
| SCHEMBL990839 | 0.72 | GRM5 (1.00) | GRM5 | |
| SCHEMBL10995127 | 0.72 | AKR1C3 (0.57) | GRM5ABL1BCRLMNA | |
| SCHEMBL10988007 | 0.71 | LMNA (0.56) | GRM5ABL1BCRLMNA | |
| SCHEMBL29944101 | 0.70 | TSHR (0.67) | GRM5LMNA | |
| SCHEMBL5364612 | 0.70 | PDK2 (0.50) | LMNA | |
| SCHEMBL10155923 | 0.69 | HPGD (0.54) | GRM5LMNA | |
| SCHEMBL990783 | 0.69 | GRM5 (1.00) | GRM5 | |
| SCHEMBL991073 | 0.69 | GRM5 (1.00) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090005363-A1 | Organic Compounds | NOVARTIS AG (CH) | 2009-01-01 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090005363-A1 | Organic Compounds | NNT, NAPRT, CHRNA5 | GRM5 680/4885ABL1 2094/4885BCR 4777/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.