SCHEMBL451390

SCHEMBL451390

OCc1ccnc(Cl)c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12173582 0.85
SCHEMBL15265157 0.83 RECQL (0.70)
SCHEMBL23152494 0.79 RECQL (0.66)
SCHEMBL1503624 0.79
SCHEMBL13177492 0.77
SCHEMBL451167 0.77
SCHEMBL451389 0.77
SCHEMBL805501 0.77
SCHEMBL937707 0.77
Hydrochloric Acid SCHEMBL7458809 0.77 LOXL2 (0.63)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 655 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119056265-A Reverse osmosis membrane, high-recovery reverse osmosis device containing reverse osmosis membrane and application of reverse osmosis membrane 杭州上拓环境科技股份有限公司 2024-12-03 CN claimed
CN-113979955-B Preparation method of heterocyclic ester compound 河南农业大学 2024-05-14 CN claimed
CN-116411037-A Preparation method of azacyclic ester compound 河南农业大学 2023-07-11 CN claimed
CN-114190189-A Method for promoting plant growth 山东元泰生物工程有限公司 2022-03-18 CN claimed
CN-113979955-A Preparation method of heterocyclic ester compound 河南农业大学 2022-01-28 CN claimed
CN-106751439-B A kind of carbinol-modified pnenolic aldehyde foam materials of 2-aminopyridine -4- and preparation method thereof 沈阳化工大学 2018-10-26 CN claimed
CN-106751439-A Carbinol-modified pnenolic aldehyde foam material of a kind of 2 aminopyridine 4 and preparation method thereof 沈阳化工大学 2017-05-31 CN claimed
CN-103664766-B Preparation method of 2-aminopyridine-4-methyl alcohol UNIV ZHEJIANG 2015-06-24 CN claimed
CN-103664766-A Preparation method of 2-aminopyridine-4-methyl alcohol UNIV ZHEJIANG 2014-03-26 CN claimed
JP-2011524881-A 2011-09-08 JP claimed
EP-2307385-A1 2 -ARYLAMINOQUINAZOLINES FOR TREATING PROLIFERATIVE DISEASES Novartis AG (CH) 2011-04-13 EP claimed
US-20100121052-A1 Novel compounds for treating proliferative diseases JAIN RAMA 2010-05-13 US claimed
WO-2009153313-A1 2 -ARYLAMINOQUINAZOLINES FOR TREATING PROLIFERATIVE DISEASES NOVARTIS AG (CH) 2009-12-23 WO claimed
JP-4243867-A None JP disclosed
EP-4142732-B1 METHODS OF USE FOR PYRIMIDINES AS FERROPORTIN INHIBITORS GLOBAL BLOOD THERAPEUTICS INC (US) 2026-04-22 EP disclosed
EP-4061812-B1 COMPOUNDS USEFUL AS INHIBITORS OF HELIOS PROTEIN BRISTOL MYERS SQUIBB CO (US) 2026-03-25 EP disclosed
JP-H04243867-A PRODUCTION OF 2-CHLORO-4-PYRIDINEMETHANOL IKEDA MOHANDOU:KK 1992-08-31 JP disclosed
US-4977267-A ANTISECRETORY AGENT FUJIREBIO KABUSHIKI KAISHA (JP) 1990-12-11 US disclosed
US-4912101-A Containing a secondary amide, suflur group and a furan ring FUJIREBIO KABUSHIKI KAISHA (JP) 1990-03-27 US disclosed
EP-0282077-A2 Pyridyloxy derivatives FUJIREBIO KABUSHIKI KAISHA (JP) 1988-09-14 EP disclosed