SCHEMBL4514248

SCHEMBL4514248

CO[SiH2]NCCN(OC)OC

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL888595 0.73
SCHEMBL888393 0.73 MEN1 (0.36)
SCHEMBL12192522 0.69
SCHEMBL27859693 0.67
SCHEMBL8925910 0.66
SCHEMBL8176534 0.59
SCHEMBL3713728 0.58
SCHEMBL7627799 0.58
SCHEMBL23405472 0.56
SCHEMBL10740953 0.56

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1166116-B1 MINIATURIZED CELL ARRAY METHODS AND APPARATUS FOR CELL-BASED SCREENING CELLOMICS INC (US) 2003-06-04 EP claimed
EP-1166116-A1 MINIATURIZED CELL ARRAY METHODS AND APPARATUS FOR CELL-BASED SCREENING Cellomics, Inc. (US) 2002-01-02 EP claimed
WO-2000060356-A1 MINIATURIZED CELL ARRAY METHODS AND APPARATUS FOR CELL-BASED SCREENING CELLOMICS, INC. (US) 2000-10-12 WO claimed
US-8231746-B1 Method and device for detection of a nitroaromatic explosive THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2012-07-31 US disclosed
US-7476510-B2 Miniaturized cell array methods and apparatus for cell-based screening CELLOMICS, INC. (US) 2009-01-13 US disclosed
US-20070166771-A1 Miniaturized cell array methods and apparatus for cell-based screening CELLOMICS, INC. (US) 2007-07-19 US disclosed
US-7160687-B1 Miniaturized cell array methods and apparatus for cell-based screening CELLOMICS, INC. (US) 2007-01-09 US disclosed
EP-1166116-B1 MINIATURIZED CELL ARRAY METHODS AND APPARATUS FOR CELL-BASED SCREENING CELLOMICS INC (US) 2003-06-04 EP disclosed
US-6548263-B1 Contacting hydroxyl groups on the substrage surface with a bifunctional molecule comprising a hydroxy-reactive group and a nucleophilic group to form a monolayer, applying stencil to the substrate to deposit cell repulsive or adhesive groups CELLOMICS, INC. 2003-04-15 US disclosed
EP-1196774-A2 MINIATURIZED CELL ARRAY METHODS AND APPARATUS FOR CELL-BASED SCREENING Cellomics, Inc. (US) 2002-04-17 EP disclosed
EP-1166116-A1 MINIATURIZED CELL ARRAY METHODS AND APPARATUS FOR CELL-BASED SCREENING Cellomics, Inc. (US) 2002-01-02 EP disclosed
WO-2001007891-A2 MINIATURIZED CELL ARRAY METHODS AND APPARATUS FOR CELL-BASED SCREENING CELLOMICS, INC. (US) 2001-02-01 WO disclosed
WO-2001007889-A2 MINIATURIZED CELL ARRAY METHODS AND APPARATUS FOR CELL-BASED SCREENING CELLOMICS, INC. (US) 2001-02-01 WO disclosed
WO-2000060356-A1 MINIATURIZED CELL ARRAY METHODS AND APPARATUS FOR CELL-BASED SCREENING CELLOMICS, INC. (US) 2000-10-12 WO disclosed