SCHEMBL888393

SCHEMBL888393

CO[SiH2]NCCN(C(C)C)C(C)C

nearest known ligand 0.36

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
ALDH1A1 P00352 1/20 0.31
HSP90AA1 P07900 1/20 0.30
HSP90AB1 P08238 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4514248 0.73
SCHEMBL5932747 0.68 MEN1 (0.48) MEN1KMT2AALDH1A1
SCHEMBL1488786 0.66 PRMT3 (0.48) MEN1KMT2AALDH1A1
SCHEMBL12192522 0.66
SCHEMBL27859693 0.64
SCHEMBL841169 0.64 MEN1 (0.50) MEN1KMT2AALDH1A1
SCHEMBL1488784 0.64 MEN1 (0.43) MEN1KMT2AALDH1A1
SCHEMBL1133203 0.63 MEN1 (0.62) MEN1KMT2AALDH1A1
Hydrochloric Acid SCHEMBL27332402 0.63 MEN1 (0.48) MEN1KMT2A
SCHEMBL13450925 0.63 KDM4E (0.39) MEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2374821-B1 MANUFACTURING METHOD OF SOLID CATALYST COMPONENT AND OF CATALYST FOR OLEFIN POLYMERIZATION TOHO TITANIUM CO LTD (JP) 2015-05-06 EP disclosed
US-8546290-B2 Solid catalyst component for olefin polymerization, manufacturing method, and catalyst and olefin polymer manufacturing method TOHO TITANIUM CO., LTD. (JP) 2013-10-01 US disclosed
US-20110269926-A1 SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, MANUFACTURING METHOD, AND CATALYST AND OLEFIN POLYMER MANUFACTURING METHOD TOHO TITANIUM CO., LTD. (JP) 2011-11-03 US disclosed