Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.59 |
| ▸ | HTR7 | P34969 | 2/20 | 0.56 |
| ▸ | HTR1A | P08908 | 1/20 | 0.56 |
| ▸ | DRD2 | P14416 | 1/20 | 0.56 |
| ▸ | HTR2A | P28223 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4514426 | 0.91 | ALDH1A1 (0.62) | ALDH1A1KDM4ESMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL7925245 | 0.91 | ALDH1A1 (0.62) | ALDH1A1KDM4ESMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL4523590 | 0.91 | ALDH1A1 (0.56) | ALDH1A1KDM4EHTR7HTR1ADRD2 | |
| SCHEMBL9342470 | 0.90 | KDM4E (0.60) | ALDH1A1KDM4EHTR7HTR1ADRD2 | |
| SCHEMBL4506995 | 0.89 | ALDH1A1 (0.59) | ALDH1A1KDM4EHTR7HTR1ADRD2 | |
| SCHEMBL4514567 | 0.87 | KDM4E (0.59) | ALDH1A1KDM4EHTR7HTR1ADRD2 | |
| SCHEMBL20794235 | 0.87 | BCHE (0.68) | ALDH1A1KDM4EHTR7HTR1ADRD2 | |
| SCHEMBL4500076 | 0.87 | ALDH1A1 (0.58) | ALDH1A1KDM4ESMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL7923817 | 0.87 | ALDH1A1 (0.58) | ALDH1A1KDM4EHTR7HTR1ADRD2 | |
| SCHEMBL4513801 | 0.87 | ALDH1A1 (0.63) | ALDH1A1KDM4ESMN1; SMN2TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260001838-A1 | NANOMATERIALS | GUIDE THERAPEUTICS LLC (US) | 2026-01-01 | — | — | US | disclosed |
| US-12435035-B2 | Nanomaterials | GUIDE THERAPEUTICS, LLC (US) | 2025-10-07 | — | — | US | disclosed |
| CN-119684140-A | Nanomaterial for the preparation of a nanoparticle | 盖德治疗有限责任公司 | 2025-03-25 | — | — | CN | disclosed |
| CN-115175894-B | Nanomaterial for the preparation of a nanoparticle | 盖德治疗有限责任公司 | 2024-09-06 | — | — | CN | disclosed |
| EP-4103542-A1 | NANOMATERIALS | Guide Therapeutics, LLC (US) | 2022-12-21 | — | — | EP | disclosed |
| CN-115175894-A | Nano material | 盖德治疗有限责任公司 | 2022-10-11 | — | — | CN | disclosed |
| US-20210230112-A1 | NANOMATERIALS | GUIDE THERAPEUTICS, LLC | 2021-07-29 | — | — | US | disclosed |
| US-20210230112-A1 | NANOMATERIALS | GUIDE THERAPEUTICS, LLC | 2021-07-29 | — | — | US | disclosed |
| US-20090258883-A1 | 1H-Indole-Pyridinecarboxamide and 1H-Indole-Piperidinecarboxamide Compounds | LES LABORATOIRES SERVIER (FR) | 2009-10-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210230112-A1 | NANOMATERIALS | NPC1, NPC1L1, FABP1 | ALDH1A1 984/4885KDM4E 4299/4885HTR7 4210/4885 |
| US-20260001838-A1 | NANOMATERIALS | SLC10A1, NPC1L1, FABP1 | ALDH1A1 619/4885KDM4E 1939/4885HTR7 4390/4885 |
| US-12435035-B2 | Nanomaterials | NPC1, NPC1L1, FABP1 | ALDH1A1 984/4885KDM4E 4299/4885HTR7 4210/4885 |
| US-20090258883-A1 | 1H-Indole-Pyridinecarboxamide and 1H-Indole-Piperidinecarboxamide Compounds | IDO1, AHR, IDO2 | ALDH1A1 370/4885KDM4E 2039/4885HTR7 194/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.