Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL9751842 | 0.96 | FFAR3 (0.54) | — | |
| Acetic Acid SCHEMBL5093045 | 0.96 | — | — | |
| Acetic Acid SCHEMBL28301301 | 0.87 | FFAR3 (0.64) | — | |
| Acetic Acid SCHEMBL1591297 | 0.87 | FFAR3 (0.64) | — | |
| Acetic Acid SCHEMBL694363 | 0.87 | — | — | |
| Bicarbonate SCHEMBL4105106 | 0.87 | — | — | |
| Acetone SCHEMBL5358085 | 0.87 | — | — | |
| Acetic Acid SCHEMBL10415847 | 0.85 | FFAR3 (0.50) | — | |
| Acetic Acid SCHEMBL11765747 | 0.85 | LMNA (0.50) | — | |
| Acetic Acid SCHEMBL10928523 | 0.85 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111246917-A | Pharmaceutical composition comprising remogliflozin and an antidiabetic drug | 格兰马克药品有限公司 | 2020-06-05 | — | — | CN | claimed |
| EP-2914687-A2 | SOLUBLE POLYMERS | THE UNIVERSITY OF LIVERPOOL (GB) | 2015-09-09 | — | — | EP | claimed |
| WO-2014068337-A2 | SOLUBLE POLYMERS | THE UNIVERSITY OF LIVERPOOL (GB) | 2014-05-08 | — | — | WO | claimed |
| CN-101695510-A | Method for extracting poplar bark lipoid | JING WANG | 2010-04-21 | — | — | CN | claimed |
| EP-4341255-A1 | MACROCYCLIC GLUCAGON-LIKE PEPTIDE 1 RECEPTOR AGONISTS | Eli Lilly and Company (US) | 2024-03-27 | — | — | EP | disclosed |
| CN-117355517-A | Macrocyclic glucagon-like peptide 1 receptor agonists | 伊莱利利公司 | 2024-01-05 | — | — | CN | disclosed |
| CN-113264945-B | Spiro derivative, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2022-11-22 | — | — | CN | disclosed |
| CN-115353667-A | Method and material for reducing waste | 李蓁蓁 | 2022-11-18 | — | — | CN | disclosed |
| CN-113264945-A | Spiro derivative, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2021-08-17 | — | — | CN | disclosed |
| CN-110753540-A | Oral pharmaceutical formulation of regagliflozin | 格兰马克药品有限公司 | 2020-02-04 | — | — | CN | disclosed |
| US-10500286-B2 | CCK2R-drug conjugates | ENDOCYTE, INC. (US) | 2019-12-10 | — | — | US | disclosed |
| EP-3334447-A1 | CCK2R-DRUG CONJUGATES | Endocyte, Inc. (US) | 2018-06-20 | — | — | EP | disclosed |
| US-20020107255-A1 | Novel piperazine derivatives | PFIZER PRODUCTS INC. | 2002-08-08 | — | — | US | disclosed |
| WO-2001072728-A2 | NOVEL PIPERAZINE DERIVATIVES | PFIZER PRODUCTS INC. (US) | 2001-10-04 | — | — | WO | disclosed |
| EP-0209435-B1 | Hydroxyalkoxy-4-phenylpropyl indole derivatives, their salts, process and intermediates for their preparation, use as medicines and compositions containing them | ROUSSEL UCLAF (FR) | 1993-11-24 | — | — | EP | disclosed |
| EP-0209435-A1 | Hydroxyalkoxy-4-phenylpropyl indole derivatives, their salts, process and intermediates for their preparation, use as medicines and compositions containing them | ROUSSEL-UCLAF (FR) | 1987-01-21 | — | — | EP | disclosed |
| EP-0074259-B1 | CATALYTIC EPOXIDATION OF OLEFINS | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1985-07-17 | — | — | EP | disclosed |
| US-4476314-A | Process for producing olefin oxides | MITSUBISHI GAS CHEMICAL CO., INC. (JP) | 1984-10-09 | — | — | US | disclosed |
| EP-0074259-A1 | Catalytic epoxidation of olefins | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1983-03-16 | — | — | EP | disclosed |
| US-4221918-A | CATALYTIC HYDROGENATION OF CARBOXYLIC ANHYDRIDES | CHEVRON RESEARCH COMPANY (US) | 1980-09-09 | — | — | US | disclosed |