Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | LPAR3 | Q9UBY5 | 7/20 | 0.57 |
| ▸ | LPAR2 | Q9HBW0 | 6/20 | 0.57 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.57 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.52 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 3/20 | 0.43 |
| ▸ | PPARD | Q03181 | 3/20 | 0.43 |
| ▸ | PPARA | Q07869 | 3/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.43 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.43 |
| ▸ | TLR2 | O60603 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4520895 | 1.00 | ALDH1A1 (0.59) | ALDH1A1LPAR3LPAR2LPAR1TSHR | |
| SCHEMBL4530011 | 1.00 | ALDH1A1 (0.59) | ALDH1A1LPAR3LPAR2LPAR1TSHR | |
| SCHEMBL4517942 | 1.00 | ALDH1A1 (0.59) | ALDH1A1LPAR3LPAR2LPAR1TSHR | |
| SCHEMBL4536430 | 1.00 | ALDH1A1 (0.59) | ALDH1A1LPAR3LPAR2LPAR1TSHR | |
| SCHEMBL4525157 | 1.00 | ALDH1A1 (0.59) | ALDH1A1LPAR3LPAR2LPAR1TSHR | |
| SCHEMBL4535481 | 1.00 | ALDH1A1 (0.59) | ALDH1A1LPAR3LPAR2LPAR1TSHR | |
| SCHEMBL4529208 | 1.00 | ALDH1A1 (0.59) | ALDH1A1LPAR3LPAR2LPAR1TSHR | |
| SCHEMBL4517953 | 1.00 | ALDH1A1 (0.59) | ALDH1A1LPAR3LPAR2LPAR1TSHR | |
| SCHEMBL4536951 | 1.00 | ALDH1A1 (0.59) | ALDH1A1LPAR3LPAR2LPAR1TSHR | |
| SCHEMBL4528491 | 1.00 | ALDH1A1 (0.59) | ALDH1A1LPAR3LPAR2LPAR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090123516-A1 | DRUG DELIVERY FROM IMPLANTS USING SELF-ASSEMBLED MONOLAYERS-THERAPEUTIC SAMS | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM | 2009-05-14 | — | — | US | disclosed |
| WO-2007019478-A2 | DRUG DELIVERY FROM IMPLANTS USING SELF-ASSEMBLED MONOLAYERS - THERAPEUTIC SAMS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2007-02-15 | — | — | WO | disclosed |