Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NGFR | P08138 | 1/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.65 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.65 |
| ▸ | MEN1 | O00255 | 3/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | HPGD | P15428 | 2/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.65 |
| ▸ | GAA | P10253 | 2/20 | 0.65 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.65 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.65 |
| ▸ | GLA | P06280 | 1/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.65 |
| ▸ | AHR | P35869 | 1/20 | 0.65 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.65 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.65 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.65 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11615435 | 0.85 | NGFR (0.67) | NGFRKDM4EGPR35MEN1KMT2A | |
| SCHEMBL11698420 | 0.84 | NGFR (0.71) | NGFRKDM4EGPR35MEN1KMT2A | |
| SCHEMBL1504031 | 0.81 | MEN1 (0.77) | NGFRKDM4EGPR35MEN1KMT2A | |
| SCHEMBL8210976 | 0.81 | NGFR (0.67) | NGFRKDM4EGPR35MEN1KMT2A | |
| SCHEMBL9452339 | 0.81 | NGFR (0.67) | NGFRKDM4EGPR35MEN1KMT2A | |
| SCHEMBL9452255 | 0.81 | NGFR (0.67) | NGFRKDM4EGPR35MEN1KMT2A | |
| SCHEMBL9452271 | 0.81 | NGFR (0.67) | NGFRKDM4EGPR35MEN1KMT2A | |
| SCHEMBL11620057 | 0.81 | KDM4E (0.72) | NGFRKDM4EGPR35MEN1KMT2A | |
| SCHEMBL11616760 | 0.80 | NGFR (0.74) | NGFRKDM4EGPR35MEN1KMT2A | |
| SCHEMBL11643685 | 0.80 | GPR35 (0.65) | NGFRKDM4EGPR35MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119285544-A | Method for separating and preparing natural 6-hydroxykynurenic acid from ginkgo leaves | 浙江理工大学绍兴生物医药研究院有限公司 | 2025-01-10 | — | — | CN | disclosed |
| WO-2023246355-A1 | GINKGO LEAF ORGANIC ACID EXTRACT, METHOD FOR PREARING SAME AND USE THEREOF | 浙江康恩贝制药股份有限公司 | 2023-12-28 | — | — | WO | disclosed |
| CN-115006435-B | Ginkgo leaf organic acid extract and preparation method and application thereof | 浙江康恩贝制药股份有限公司 | 2023-11-28 | — | — | CN | disclosed |
| CN-114366761-B | Preparation method of ginkgo leaf extract rich in organic acid | 江苏得乐康生物科技有限公司 | 2022-11-01 | — | — | CN | disclosed |
| CN-115006435-A | Ginkgo leaf organic acid extract and preparation method and application thereof | 浙江康恩贝制药股份有限公司 | 2022-09-06 | — | — | CN | disclosed |
| CN-114366761-A | Preparation method of ginkgo leaf extract rich in organic acid | 江苏得乐康生物科技有限公司 | 2022-04-19 | — | — | CN | disclosed |
| CN-103784448-B | A kind of preparation method of natural 6-HKA extract and application thereof | ZHEJIANG CONBA PHARMACEUTICAL CO., LTD. (CN) | 2015-11-18 | — | — | CN | disclosed |
| US-20090012118-A1 | Kynurenic Acid Amide Derivatives as Nr2b Receptor Antagoni | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 2009-01-08 | — | — | US | disclosed |
| CN-1989127-A | Kynurenic acid amide derivatives as NR2B receptor antagonists | RICHTER GEDEON VEGYESZET (HU) | 2007-06-27 | — | — | CN | disclosed |
| EP-1771436-A1 | KYNURENIC ACID AMIDE DERIVATIVES AS NR2B RECEPTOR ANTAGONISTS | Richter Gedeon Vegy Szeti Gy R Rt. (HU) | 2007-04-11 | — | — | EP | disclosed |
| WO-2006010967-A1 | KYNURENIC ACID AMIDE DERIVATIVES AS NR2B RECEPTOR ANTAGONISTS | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 2006-02-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090012118-A1 | Kynurenic Acid Amide Derivatives as Nr2b Receptor Antagoni | GRIN1, GRIN2A, GRIN2B | NGFR 331/4885KDM4E 2737/4885GPR35 50/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.