SCHEMBL4517033

SCHEMBL4517033

CCO[Si](CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC(=O)O)(OCC)OCC

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 7/20 0.50
PPARG P37231 7/20 0.50
PPARD Q03181 7/20 0.50
PPARA Q07869 7/20 0.50
HDAC11 Q96DB2 5/20 0.50
TSHR P16473 5/20 0.50
PTPN1 P18031 3/20 0.50
ALDH1A1 P00352 3/20 0.50
TLR2 O60603 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
FABP4 P15090 2/20 0.50
KMT2A Q03164 2/20 0.50
SLC22A6 Q4U2R8 1/20 0.50
SLC22A8 Q8TCC7 1/20 0.50
MEN1 O00255 1/20 0.50
ESR1 P03372 1/20 0.50
ALOX15 P16050 1/20 0.50
PDE4A P27815 1/20 0.50
PDE3A Q14432 1/20 0.50
HSD17B10 Q99714 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4518551 1.00 GPR84 (0.50) GPR84PPARGPPARDPPARAHDAC11
SCHEMBL4528271 1.00 GPR84 (0.50) GPR84PPARGPPARDPPARAHDAC11
SCHEMBL4522923 1.00 GPR84 (0.50) GPR84PPARGPPARDPPARAHDAC11
SCHEMBL1054786 1.00 GPR84 (0.50) GPR84PPARGPPARDPPARAHDAC11
SCHEMBL4532402 1.00 GPR84 (0.50) GPR84PPARGPPARDPPARAHDAC11
SCHEMBL4531810 1.00 GPR84 (0.50) GPR84PPARGPPARDPPARAHDAC11
SCHEMBL4530810 1.00 GPR84 (0.50) GPR84PPARGPPARDPPARAHDAC11
SCHEMBL4528299 1.00 GPR84 (0.50) GPR84PPARGPPARDPPARAHDAC11
SCHEMBL4528611 1.00 GPR84 (0.50) GPR84PPARGPPARDPPARAHDAC11
SCHEMBL4532550 1.00 GPR84 (0.50) GPR84PPARGPPARDPPARAHDAC11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090123516-A1 DRUG DELIVERY FROM IMPLANTS USING SELF-ASSEMBLED MONOLAYERS-THERAPEUTIC SAMS THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM 2009-05-14 US disclosed
WO-2007019478-A2 DRUG DELIVERY FROM IMPLANTS USING SELF-ASSEMBLED MONOLAYERS - THERAPEUTIC SAMS BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2007-02-15 WO disclosed