Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 16/20 | 0.52 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.47 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4515712 | 0.90 | KCNH2 (0.54) | KCNH2 | |
| SCHEMBL4512787 | 0.90 | KCNH2 (0.54) | KCNH2 | |
| SCHEMBL4509808 | 0.86 | KCNH2 (0.41) | KCNH2 | |
| SCHEMBL4499945 | 0.82 | KCNH2 (0.64) | KCNH2 | |
| SCHEMBL4775783 | 0.81 | KCNH2 (0.44) | KCNH2 | |
| SCHEMBL14341214 | 0.80 | KCNH2 (0.67) | KCNH2KCNQ1CACNA1C | |
| SCHEMBL4510282 | 0.80 | KCNH2 (0.64) | KCNH2KCNQ1CACNA1C | |
| SCHEMBL4501354 | 0.80 | KCNH2 (0.43) | KCNH2 | |
| SCHEMBL3376441 | 0.78 | KCNH2 (0.55) | KCNH2KCNQ1CACNA1C | |
| SCHEMBL3376444 | 0.78 | KCNH2 (0.55) | KCNH2KCNQ1CACNA1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090131444-A1 | Aminopiperidine Quinolines and Their Azaisosteric Analogues with Antibacterial Activity | ASTRAZENECA AB (SE) | 2009-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090131444-A1 | Aminopiperidine Quinolines and Their Azaisosteric Analogues with Antibacterial Activity | AAAS, AMPD2, AMPD3 | KCNH2 1951/4885KCNQ1 279/4885CACNA1C 4366/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.