Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.42 |
| ▸ | S100A4 | P26447 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 3/20 | 0.40 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.40 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.39 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | CLK1 | P49759 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL203228 | 0.80 | HTT (0.47) | MEN1KMT2ATDP1ALDH1A1HTT | |
| SCHEMBL2707298 | 0.79 | KMT2A (0.55) | MEN1KMT2AKDM4EHSP90AA1HSP90AB1 | |
| SCHEMBL27747272 | 0.76 | KDM4E (0.36) | MEN1KMT2AKDM4EHSP90AA1SLC40A1 | |
| SCHEMBL17776539 | 0.73 | MEN1 (0.64) | MEN1KMT2AKDM4EATMSLC40A1 | |
| SCHEMBL6143237 | 0.73 | SMN1; SMN2 (0.63) | MEN1KMT2AKDM4ETDP1ALDH1A1 | |
| SCHEMBL28419223 | 0.72 | ATM (0.59) | MEN1KMT2AKDM4EHSP90AA1ATM | |
| SCHEMBL14657710 | 0.72 | KDM4E (0.42) | MEN1KMT2AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL17597171 | 0.72 | KDM4E (0.57) | MEN1KMT2AKDM4EHSP90AA1ATM | |
| SCHEMBL28419838 | 0.71 | SLC40A1 (0.54) | MEN1KMT2AATMSLC40A1KDR | |
| SCHEMBL29918706 | 0.70 | TDP1 (0.71) | MEN1KMT2AKDM4ESLC40A1KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090240055-A1 | Method for 1H-Imidazo[4,5-C] Pyridines and Analogs Thereof | KREPSKI LARRY R | 2009-09-24 | — | — | US | disclosed |
| CN-101312975-A | Method for 1h-imidazo[4,5-c]pyridines and analogs thereof | COLEY PHARM GROUP INC (US) | 2008-11-26 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090240055-A1 | Method for 1H-Imidazo[4,5-C] Pyridines and Analogs Thereof | CYP4B1, CYP4F8, CYP4X1 | MEN1 205/4885KMT2A 2015/4885KDM4E 503/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.