SCHEMBL4518306

SCHEMBL4518306

N#CC(C#N)CCC(F)=C(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL820002 0.67 TSHR (0.33)
SCHEMBL9487362 0.67 FOLH1 (0.46)
SCHEMBL4096637 0.67 TSHR (0.38)
SCHEMBL4107685 0.65
SCHEMBL12736693 0.65 CA1 (0.42)
SCHEMBL27850966 0.65 PMP22 (0.44)
SCHEMBL2429511 0.65 ALDH1A1 (0.43)
SCHEMBL28138919 0.64
SCHEMBL819370 0.62 TSHR (0.30)
SCHEMBL21874813 0.62 TSHR (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090136551-A1 Substituted Dicyanoalkanes For Combating Animal Pests BASF AKTIENGESELLSCHAFT (DE) 2009-05-28 US disclosed
EP-1385817-B1 MALONONITRILE COMPOUNDS AND THEIR USE AS PESTICIDES SUMITOMO CHEMICAL CO (JP) 2008-12-03 EP disclosed
US-20080227635-A1 Dicyano Alkanoic Acid Amides for Combating Animal Pests BASF AKTIENGESELLSCHAFT (DE) 2008-09-18 US disclosed
US-7402691-B2 Malononitrile compounds and their use as pesticides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-07-22 US disclosed
US-7402691-B2 Malononitrile compounds and their use as pesticides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-07-22 US disclosed
EP-1916895-A1 DICYANO ALKANOIC ACID AMIDES FOR COMBATING ANIMAL PESTS BASF SE (DE) 2008-05-07 EP disclosed
EP-1912958-A1 SUBSTITUTED MALONONITRILE COMPOUNDS FOR COMBATING ANIMAL PESTS BASF SE (DE) 2008-04-23 EP disclosed
WO-2007017414-A1 SUBSTITUTED MALONONITRILE COMPOUNDS FOR COMBATING ANIMAL PESTS BASF SE (DE) 2007-02-15 WO disclosed
WO-2007014899-A1 DICYANO ALKANOIC ACID AMIDES FOR COMBATING ANIMAL PESTS BASF SE (DE) 2007-02-08 WO disclosed
WO-2006122949-A1 MALONONITRILES AND THEIR USE AS PESTICIDES BASF AKTIENGESELLSCHAFT (DE) 2006-11-23 WO disclosed
EP-1521528-B1 MALONONITRILE COMPOUNDS AND THEIR USE AS PESTICIDES SUMITOMO CHEMICAL CO (JP) 2006-11-22 EP disclosed
US-7026340-B2 Malononitrile compounds and their use as pesticides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-04-11 US disclosed
US-7011838-B2 Malononitrile compounds and their use as pesticides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-03-14 US disclosed
US-20050209323-A1 Malononitrile compounds and their use as pesticides OTAKA KEN 2005-09-22 US disclosed
US-20050176784-A1 Malononitrile compounds and their use as pesticides SUMITOMO CHECMICAL COMPANY, LIMITED (JP) 2005-08-11 US disclosed
EP-1521528-A1 MALONONITRILE COMPOUNDS AND THEIR USE AS PESTICIDES Sumitomo Chemical Company, Limited (JP) 2005-04-13 EP disclosed
US-20040138065-A1 Malononitrile compounds and their use as pesticides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-07-15 US disclosed
EP-1385817-A2 MALONONITRILE COMPOUNDS AND THEIR USE AS PESTICIDES SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2004-02-04 EP disclosed
WO-2004006677-A1 MALONONITRILE COMPOUNDS AND THEIR USE AS PESTICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-01-22 WO disclosed
WO-2002090320-A2 MALONONITRILE COMPOUNDS AND THEIR USE AS PESTICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-11-14 WO disclosed