Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 20/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4515602 | 0.97 | F10 (0.80) | F10 | |
| Formic Acid SCHEMBL4508155 | 0.93 | F10 (0.73) | F10 | |
| Formic Acid SCHEMBL4505505 | 0.91 | F10 (0.72) | F10 | |
| Formic Acid SCHEMBL6365065 | 0.90 | F10 (0.94) | F10 | |
| SCHEMBL4518694 | 0.90 | F10 (0.77) | F10 | |
| SCHEMBL13971675 | 0.88 | F10 (0.77) | F10 | |
| Formic Acid SCHEMBL6367624 | 0.87 | F10 (0.77) | F10 | |
| Formic Acid SCHEMBL6361860 | 0.83 | F10 (0.71) | F10 | |
| SCHEMBL4518598 | 0.83 | F10 (0.58) | F10 | |
| SCHEMBL6361859 | 0.81 | F10 (0.68) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7482374-B2 | Pyrrolidine-2-ones as Factor Xa inhibitors | GLAXO GROUP LIMITED (GB) | 2009-01-27 | — | — | US | disclosed |
| US-20060167079-A1 | Pyrrolidine -2-ones as factor xa inhibitors | GLAXO GROUP LIMITED (GB) | 2006-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060167079-A1 | Pyrrolidine -2-ones as factor xa inhibitors | TFPI, F2, F11 | F10 10/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.