SCHEMBL4519322

SCHEMBL4519322

CCNCCCCCCCCCC[SiH](O)O

nearest known ligand 0.52

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 2/20 0.52
TSHR P16473 2/20 0.52
CYP1A2 P05177 1/20 0.52
KDM1A O60341 5/20 0.48
MEN1 O00255 1/20 0.48
GLA P06280 1/20 0.48
KMT2A Q03164 1/20 0.48
SAT1 P21673 3/20 0.39
ALDH1A1 P00352 1/20 0.36
HRH4 Q9H3N8 1/20 0.34
HRH3 Q9Y5N1 1/20 0.34
S1PR2 O95136 5/20 0.32
S1PR4 O95977 5/20 0.32
S1PR1 P21453 5/20 0.32
S1PR3 Q99500 5/20 0.32
ANPEP P15144 1/20 0.32
ERAP2 Q6P179 1/20 0.32
S1PR5 Q9H228 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4527294 0.90
SCHEMBL4521500 0.84 TSHR (0.59) TSHRALDH1A1S1PR2S1PR4S1PR1
SCHEMBL4522872 0.79
SCHEMBL4530171 0.79 TSHR (0.59) TSHRALDH1A1S1PR2S1PR4S1PR1
SCHEMBL15004569 0.79 TSHR (0.59) TSHRALDH1A1S1PR2S1PR4S1PR1
SCHEMBL331540 0.79 CYP2C19 (0.80) CYP2C19TSHRCYP1A2KDM1AMEN1
SCHEMBL13893419 0.79 CYP2C19 (0.80) CYP2C19TSHRCYP1A2KDM1AMEN1
SCHEMBL7089751 0.79 CYP2C19 (0.80) CYP2C19TSHRCYP1A2KDM1AMEN1
SCHEMBL19620508 0.79 CYP2C19 (0.80) CYP2C19TSHRCYP1A2KDM1AMEN1
SCHEMBL331498 0.79 CYP2C19 (0.80) CYP2C19TSHRCYP1A2KDM1AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7507480-B2 Corrosion-resistant metal surfaces BROOKHAVEN SCIENCE ASSOCIATES, LLC (US) 2009-03-24 US disclosed
US-20060269760-A1 Corrosion-resistant metal surfaces ENERGY, UNITED STATES DEPARTMENT OF 2006-11-30 US disclosed