SCHEMBL4519903

SCHEMBL4519903

CCO[Si](OCC)(OCC)c1ccccn1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNA5 P22460 2/20 0.38
KCNH2 Q12809 1/20 0.38
GRM5 P41594 1/20 0.38
LMNA P02545 2/20 0.37
CYP2D6 P10635 2/20 0.36
CYP1A2 P05177 2/20 0.36
CYP19A1 P11511 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
KCNE1 P15382 1/20 0.36
KDM4E B2RXH2 3/20 0.36
POLB P06746 1/20 0.36
CCR1 P32246 1/20 0.36
CCR5 P51681 1/20 0.36
CCR8 P51685 1/20 0.36
METAP1 P53582 1/20 0.36
BLM P54132 1/20 0.36
HIF1A Q16665 1/20 0.36
DOHH Q9BU89 1/20 0.36
P4HTM Q9NXG6 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18328033 0.83 NOS3 (0.38) KCNA5KCNH2GRM5LMNACYP2D6
SCHEMBL12615705 0.81 KDM4E (0.53) LMNACYP2D6CYP1A2CYP19A1CYP2C9
SCHEMBL31010180 0.76 KDM4E (0.40) LMNACYP1A2KDM4EPOLBCCR1
SCHEMBL1134135 0.76 KDM4E (0.40) LMNACYP1A2KDM4EPOLBCCR1
SCHEMBL29968555 0.71
SCHEMBL152133 0.71
SCHEMBL16166168 0.71 KCNA5 (0.41) KCNA5KCNH2LMNACYP2D6CYP1A2
SCHEMBL12614987 0.71 BTK (0.38) LMNACYP1A2KDM4ECCR1CCR5
SCHEMBL28316504 0.71 CYP2D6 (0.35) CYP2D6CYP19A1CYP2C9CYP2C19KDM4E
SCHEMBL28812809 0.71 KCNA5 (0.39) KCNA5KCNH2GRM5LMNACYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250229250-A1 MAGNETIC MESOPOROUS SILICA-BASED (MMPS) MATERIALS Université de Bourgogne (FR) 2025-07-17 US disclosed
EP-4504663-A1 MAGNETIC MESOPOROUS SILICA-BASED (MMS) MATERIALS Université de Bourgogne (FR) 2025-02-12 EP disclosed
WO-2023194681-A1 MAGNETIC MESOPOROUS SILICA-BASED (MMS) MATERIALS Université de Bourgogne (FR) 2023-10-12 WO disclosed
US-11028256-B2 Silica-containing rubber compositions containing specified coupling agents and related methods BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) 2021-06-08 US disclosed
US-20200123349-A1 SILICA-CONTAINING RUBBER COMPOSITIONS CONTAINING SPECIFIED COUPLING AGENTS AND RELATED METHODS BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) 2020-04-23 US disclosed
US-20170247532-A1 SILICA-CONTAINING RUBBER COMPOSITIONS CONTAINING SPECIFIED COUPLING AGENTS AND RELATED METHODS BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC 2017-08-31 US disclosed
EP-3197950-A1 SILICA-CONTAINING RUBBER COMPOSITIONS CONTAINING SPECIFIED COUPLING AGENTS AND RELATED METHODS Bridgestone Americas Tire Operations, LLC (US) 2017-08-02 EP disclosed
WO-2016048935-A1 SILICA-CONTAINING RUBBER COMPOSITIONS CONTAINING SPECIFIED COUPLING AGENTS AND RELATED METHODS BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) 2016-03-31 WO disclosed
US-9093279-B2 Thin film forming composition for lithography containing titanium and silicon NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2015-07-28 US disclosed
US-9023588-B2 Resist underlayer film forming composition containing silicon having nitrogen-containing ring NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2015-05-05 US disclosed
US-20120315765-A1 RESIST UNDERLAYER FILM FORMING COMPOSITION CONTAINING SILICON HAVING NITROGEN-CONTAINING RING NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2012-12-13 US disclosed
US-20090076316-A1 PROCESS FOR PRODUCTION OF AROMATIC HYDROCARBON Ichikawa, Masaru (JP) 2009-03-19 US disclosed
CN-101115701-A Process for production of aromatic hydrocarbon MASARU ICHIKAWA (JP) 2008-01-30 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120315765-A1 RESIST UNDERLAYER FILM FORMING COMPOSITION CONTAINING SILICON HAVING NITROGEN-CONTAINING RING SRSF1, SRSF7, SRRM2 KCNA5 1820/4885KCNH2 456/4885GRM5 4334/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.