Methacrylic Acid

Methacrylic Acid

SCHEMBL452014

C=C(C)C(=O)NCCCN(C)C.C=C(C)C(=O)O

nearest known ligand 0.51

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.51
DNM1 Q05193 1/20 0.44
LMNA P02545 1/20 0.42
PAOX Q6QHF9 1/20 0.42
HPGD P15428 1/20 0.39
POLB P06746 1/20 0.37
ALDH1A1 P00352 2/20 0.36
MEN1 O00255 1/20 0.36
HTT P42858 1/20 0.36
KMT2A Q03164 1/20 0.36
P2RX4 Q99571 1/20 0.36
ALOX15 P16050 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL9438497 0.95 KDM4E (0.53) KDM4EDNM1LMNAPAOXHPGD
Bicarbonate SCHEMBL9017530 0.95 KDM4E (0.53) KDM4EDNM1LMNAPAOXHPGD
SCHEMBL21954 0.94 KDM4E (0.56) KDM4EDNM1LMNAPAOXHPGD
Acetone SCHEMBL28357455 0.93 KDM4E (0.54) KDM4EDNM1LMNAPAOXHPGD
Hydrochloric Acid SCHEMBL111099 0.93 KDM4E (0.54) KDM4EDNM1LMNAPAOXHPGD
Ammonia Solution, Strong SCHEMBL23532663 0.93 KDM4E (0.54) KDM4EDNM1LMNAPAOXHPGD
Chloromethane SCHEMBL1655207 0.91 KDM4E (0.53) KDM4EDNM1LMNAPAOXHPGD
SCHEMBL5052709 0.91 KDM4E (0.53) KDM4EDNM1LMNAPAOXHPGD
Hydrochloric Acid SCHEMBL29083386 0.91 KDM4E (0.53) KDM4EDNM1LMNAPAOXHPGD
Chloromethane SCHEMBL8844942 0.91 KDM4E (0.53) KDM4EDNM1LMNAPAOXHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2616169-A2 CHROMATOGRAPHY MEMBRANES FOR THE PURIFICATION OF CHIRAL COMPOUNDS Natrix Separations Inc. (CA) 2013-07-24 EP claimed
EP-2499192-A1 HYDROPHOBIC INTERACTION CHROMATOGRAPHY MEMBRANES, AND METHODS OF USE THEREOF Natrix Separations Inc. (CA) 2012-09-19 EP claimed
WO-2012037101-A2 CHROMATOGRAPHY MEMBRANES FOR THE PURIFICATION OF CHIRAL COMPOUNDS NATRIX SEPARATIONS INC. (CA) 2012-03-22 WO claimed
US-20120064601-A1 Chromatography Membranes for the Purification of Chiral Compounds NATRIX SEPARATIONS INC. (CA) 2012-03-15 US claimed
US-20110117626-A1 Hydrophobic Interaction Chromatography Membranes, and Methods of Use Thereof NATRIX SEPARATIONS INC. (CA) 2011-05-19 US claimed
WO-2011058439-A1 HYDROPHOBIC INTERACTION CHROMATOGRAPHY MEMBRANES, AND METHODS OF USE THEREOF NATRIX SEPARATIONS, INC. (CA) 2011-05-19 WO claimed
CN-114013386-B Stamping, in particular for permanently closing holes 德莎欧洲股份公司 2024-04-16 CN disclosed
US-20200069602-A1 CHROMATOGRAPHIC MEDIA FOR STORAGE AND DELIVERY OF THERAPEUTIC BIOLOGICS AND SMALL MOLECULES MERCK MILLIPORE LTD. (IE) 2020-03-05 US disclosed
EP-2804634-B1 CHROMATOGRAPHIC MEDIA FOR STORAGE AND DELIVERY OF THERAPEUTIC BIOLOGICS AND SMALL MOLECULES NATRIX SEPARATIONS INC (CA) 2019-08-28 EP disclosed
EP-2804634-A1 CHROMATOGRAPHIC MEDIA FOR STORAGE AND DELIVERY OF THERAPEUTIC BIOLOGICS AND SMALL MOLECULES Natrix Separations Inc. (CA) 2014-11-26 EP disclosed
WO-2013109825-A1 CHROMATOGRAPHIC MEDIA FOR STORAGE AND DELIVERY OF THERAPEUTIC BIOLOGICS AND SMALL MOLECULES NATRIX SEPARATIONS INC. (CA) 2013-07-25 WO disclosed
US-20130189322-A1 Chromatographic Media for Storage and Delivery of Therapeutic Biologics and Small Molecules NATRIX SEPARATIONS INC. (CA) 2013-07-25 US disclosed
EP-2616169-A2 CHROMATOGRAPHY MEMBRANES FOR THE PURIFICATION OF CHIRAL COMPOUNDS Natrix Separations Inc. (CA) 2013-07-24 EP disclosed
EP-2499192-A1 HYDROPHOBIC INTERACTION CHROMATOGRAPHY MEMBRANES, AND METHODS OF USE THEREOF Natrix Separations Inc. (CA) 2012-09-19 EP disclosed
WO-2012037101-A2 CHROMATOGRAPHY MEMBRANES FOR THE PURIFICATION OF CHIRAL COMPOUNDS NATRIX SEPARATIONS INC. (CA) 2012-03-22 WO disclosed
US-20120064601-A1 Chromatography Membranes for the Purification of Chiral Compounds NATRIX SEPARATIONS INC. (CA) 2012-03-15 US disclosed
US-20110117626-A1 Hydrophobic Interaction Chromatography Membranes, and Methods of Use Thereof NATRIX SEPARATIONS INC. (CA) 2011-05-19 US disclosed
WO-2011058439-A1 HYDROPHOBIC INTERACTION CHROMATOGRAPHY MEMBRANES, AND METHODS OF USE THEREOF NATRIX SEPARATIONS, INC. (CA) 2011-05-19 WO disclosed