Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.53 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.45 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL9438497 | 0.96 | KDM4E (0.53) | KDM4EDNM1PAOXLMNAHPGD | |
| SCHEMBL21954 | 0.96 | KDM4E (0.56) | KDM4EDNM1PAOXLMNAHPGD | |
| Methacrylic Acid SCHEMBL452014 | 0.95 | KDM4E (0.51) | KDM4EDNM1PAOXLMNAHPGD | |
| Ammonia Solution, Strong SCHEMBL23532663 | 0.94 | KDM4E (0.54) | KDM4EDNM1PAOXLMNAHPGD | |
| Acetone SCHEMBL28357455 | 0.94 | KDM4E (0.54) | KDM4EDNM1PAOXLMNAHPGD | |
| Hydrochloric Acid SCHEMBL111099 | 0.94 | KDM4E (0.54) | KDM4EDNM1PAOXLMNAHPGD | |
| Chloromethane SCHEMBL1655207 | 0.93 | KDM4E (0.53) | KDM4EDNM1PAOXLMNAHPGD | |
| SCHEMBL5052709 | 0.93 | KDM4E (0.53) | KDM4EDNM1PAOXLMNAHPGD | |
| Hydrochloric Acid SCHEMBL29083386 | 0.93 | KDM4E (0.53) | KDM4EDNM1PAOXLMNAHPGD | |
| Chloromethane SCHEMBL8844942 | 0.93 | KDM4E (0.53) | KDM4EDNM1PAOXLMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5525692-A | SALT FORMING AN ACRYLIC ESTER OR AMIDE WITH CARBONIC ACID, FORMING AN AMINE SALT CARBONATE MONOMER BEFORE HOMO OR CO-POLYMERIZING, THEN DECARBOXYLATION | KOHJIN CO., LTD. (JP) | 1996-06-11 | — | — | US | disclosed |
| EP-0656372-A1 | SLUDGE DEHYDRATING AGENT | KOHJIN CO. Ltd. (JP) | 1995-06-07 | — | — | EP | disclosed |