SCHEMBL4520388

SCHEMBL4520388

Sc1ccc2cc3ccccc3cc2c1S

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.46
HSD17B10 Q99714 6/20 0.46
HIF1A Q16665 2/20 0.46
CYP1B1 Q16678 1/20 0.46
KDM4E B2RXH2 3/20 0.38
GAA P10253 2/20 0.38
TDP1 Q9NUW8 3/20 0.38
CYP3A4 P08684 3/20 0.38
ALOX15 P16050 1/20 0.38
CASP1 P29466 1/20 0.38
CASP7 P55210 1/20 0.38
HBB P68871 1/20 0.38
CYP1A2 P05177 5/20 0.38
ERBB2 P04626 1/20 0.38
FYN P06241 1/20 0.38
MAOA P21397 1/20 0.38
ACHE P22303 1/20 0.38
AHR P35869 1/20 0.38
CYP2A6 P11509 5/20 0.36
TSHR P16473 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25391909 0.83 ALDH1A1 (0.35) ALDH1A1HSD17B10HIF1ACYP1B1
SCHEMBL3630050 0.79 ALDH1A1 (0.48) ALDH1A1HSD17B10HIF1ACYP1B1KDM4E
SCHEMBL11838582 0.78 ALDH1A1 (0.45) ALDH1A1HSD17B10HIF1ACYP1B1KDM4E
SCHEMBL17796881 0.78 ALDH1A1 (0.43) ALDH1A1HSD17B10HIF1ACYP1B1KDM4E
SCHEMBL467413 0.78 HSD17B10 (0.55) ALDH1A1HSD17B10HIF1ACYP1B1TDP1
SCHEMBL4848746 0.77 ALDH1A1 (0.72) ALDH1A1HSD17B10HIF1ACYP1B1KDM4E
SCHEMBL4853659 0.77 ALDH1A1 (0.72) ALDH1A1HSD17B10HIF1ACYP1B1KDM4E
SCHEMBL23664 0.77 ALDH1A1 (0.72) ALDH1A1HSD17B10HIF1ACYP1B1KDM4E
SCHEMBL29532882 0.77 ALDH1A1 (0.72) ALDH1A1HSD17B10HIF1ACYP1B1KDM4E
SCHEMBL513014 0.76 ALDH1A1 (0.45) ALDH1A1HSD17B10HIF1ACYP1B1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090101892-A1 Organic underlayers that improve the performance of organic semiconductors INTERNATIONAL BUSINESS MACHINES CORPORATION 2009-04-23 US claimed
US-7285440-B2 Organic underlayers that improve the performance of organic semiconductors INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2007-10-23 US claimed
US-20040161873-A1 Organic underlayers that improve the performance of organic semiconductors INTERNATIONAL BUSINESS MACHINES CORPORATION 2004-08-19 US claimed
EP-2851386-B1 RESIN COMPOSITION FOR OPTICAL STEREOLITHOGRAPHY CMET INC (JP) 2017-08-16 EP disclosed
US-9416220-B2 Resin composition for optical stereolithography CMET INC. (JP) 2016-08-16 US disclosed
US-20150158971-A1 RESIN COMPOSITION FOR OPTICAL STEREOLITHOGRAPHY CMET INC. (JP) 2015-06-11 US disclosed
EP-2851386-A1 RESIN COMPOSITION FOR OPTICAL STEREOLITHOGRAPHY Cmet Inc. (JP) 2015-03-25 EP disclosed