Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKD3 | O94806 | 2/20 | 0.51 |
| ▸ | PRKD1 | Q15139 | 2/20 | 0.51 |
| ▸ | PRKD2 | Q9BZL6 | 2/20 | 0.51 |
| ▸ | GRM4 | Q14833 | 12/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CCNC | P24863 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4520412 | 1.00 | PRKD3 (0.51) | PRKD3PRKD1PRKD2GRM4KCNH2 | |
| SCHEMBL4520417 | 1.00 | PRKD3 (0.51) | PRKD3PRKD1PRKD2GRM4KCNH2 | |
| SCHEMBL4508525 | 0.87 | PRKD3 (0.67) | PRKD3PRKD1PRKD2KCNH2 | |
| SCHEMBL4508530 | 0.87 | PRKD3 (0.67) | PRKD3PRKD1PRKD2KCNH2 | |
| SCHEMBL4508519 | 0.87 | PRKD3 (0.67) | PRKD3PRKD1PRKD2KCNH2 | |
| SCHEMBL4505230 | 0.84 | PRKD3 (0.44) | PRKD3PRKD1PRKD2 | |
| SCHEMBL4505243 | 0.84 | PRKD3 (0.44) | PRKD3PRKD1PRKD2 | |
| SCHEMBL4505238 | 0.84 | PRKD3 (0.44) | PRKD3PRKD1PRKD2 | |
| SCHEMBL4513736 | 0.79 | PRKD3 (0.51) | PRKD3PRKD1PRKD2MAPK1 | |
| SCHEMBL4513754 | 0.79 | PRKD3 (0.51) | PRKD3PRKD1PRKD2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090247519-A1 | AMINO-ETHYL-AMINO-ARYL (AEAA) COMPOUNDS AND THEIR USE | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2009-10-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090247519-A1 | AMINO-ETHYL-AMINO-ARYL (AEAA) COMPOUNDS AND THEIR USE | PKD2, PKD1, AADAT | PRKD3 9/4885PRKD1 49/4885PRKD2 18/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.