Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4528247 | 0.96 | CNR1 (0.70) | CNR1CNR2 | |
| SCHEMBL4519105 | 0.91 | CNR1 (0.71) | CNR1CNR2 | |
| SCHEMBL4519724 | 0.85 | CNR1 (0.77) | CNR1CNR2 | |
| SCHEMBL4910954 | 0.84 | CNR1 (0.76) | CNR1CNR2 | |
| SCHEMBL1985356 | 0.83 | CNR1 (1.00) | CNR1CNR2 | |
| SCHEMBL1984417 | 0.83 | CNR1 (1.00) | CNR1CNR2 | |
| SCHEMBL1983499 | 0.82 | CNR1 (0.98) | CNR1CNR2 | |
| SCHEMBL4910530 | 0.82 | CNR1 (0.73) | CNR1CNR2 | |
| SCHEMBL27785524 | 0.81 | CNR1 (0.67) | CNR1CNR2 | |
| SCHEMBL4508744 | 0.81 | CNR2 (0.70) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090042864-A2 | PYRAZOLE COMPOUNDS | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2009-02-12 | — | — | US | disclosed |
| US-20090042864-A2 | PYRAZOLE COMPOUNDS | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2009-02-12 | — | — | US | disclosed |
| US-20090042864-A2 | PYRAZOLE COMPOUNDS | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2009-02-12 | — | — | US | disclosed |
| US-20080090809-A1 | PYRAZOLE COMPOUNDS | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2008-04-17 | — | — | US | disclosed |
| US-20080090809-A1 | PYRAZOLE COMPOUNDS | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2008-04-17 | — | — | US | disclosed |
| US-20080090809-A1 | PYRAZOLE COMPOUNDS | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2008-04-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090042864-A2 | PYRAZOLE COMPOUNDS | CNR2, CNR1, GPR18 | CNR1 2/4885CNR2 1/4885 |
| US-20080090809-A1 | PYRAZOLE COMPOUNDS | CNR2, CNR1, GPR18 | CNR1 2/4885CNR2 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.