O-Xylene

O-Xylene

SCHEMBL452170

Cc1ccccc1.Cc1ccccc1C

nearest known ligand 0.79

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ACHE P22303 5/20 0.79
TSHR P16473 4/20 0.79
LMNA P02545 1/20 0.79
ALOX12 P18054 1/20 0.79
TDP1 Q9NUW8 2/20 0.47
HPGD P15428 1/20 0.46
ALDH1A1 P00352 4/20 0.45
CA1 P00915 2/20 0.45
CA2 P00918 2/20 0.45
CA7 P43166 2/20 0.45
CA9 Q16790 2/20 0.45
CYP3A4 P08684 1/20 0.43
CYP1A2 P05177 3/20 0.42
CYP2A6 P11509 2/20 0.42
CES2 O00748 1/20 0.42
CES1 P23141 1/20 0.42
CYP2C19 P33261 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
O-Xylene SCHEMBL9481519 1.00 ACHE (0.79) ACHETSHRLMNAALOX12TDP1
O-Xylene SCHEMBL10956434 1.00 ACHE (0.79) ACHETSHRLMNAALOX12TDP1
O-Xylene SCHEMBL11765114 1.00 ACHE (0.79) ACHETSHRLMNAALOX12TDP1
O-Xylene SCHEMBL11405236 1.00 ACHE (0.79) ACHETSHRLMNAALOX12TDP1
O-Xylene SCHEMBL1088985 1.00 ACHE (0.79) ACHETSHRLMNAALOX12TDP1
O-Xylene SCHEMBL10822510 1.00 ACHE (0.79) ACHETSHRLMNAALOX12TDP1
O-Xylene SCHEMBL8910096 1.00 ACHE (0.79) ACHETSHRLMNAALOX12TDP1
O-Xylene SCHEMBL11240856 1.00 ACHE (0.79) ACHETSHRLMNAALOX12TDP1
O-Xylene SCHEMBL11209551 1.00 ACHE (0.79) ACHETSHRLMNAALOX12TDP1
O-Xylene SCHEMBL9268455 1.00 ACHE (0.79) ACHETSHRLMNAALOX12TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1265 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4251711-A1 INTEGRATED PROCESS WITH A DEASPHALTING COLUMN FOR CRUDE OIL DIRECT CATALYTIC UPGRADING Saudi Arabian Oil Company (SA) 2023-10-04 EP claimed
EP-3317020-B1 IMPROVED CATALYTIC FAST PYROLYSIS PROCESS WITH IMPURITY REMOVAL ANELLOTECH INC (US) 2020-01-29 EP claimed
US-10336628-B2 Catalytic fast pyrolysis process with impurity removal ANELLOTECH, INC. (US) 2019-07-02 US claimed
CN-109574899-A A kind of refining methd of ertapenem side chain 江西如益科技发展有限公司 2019-04-05 CN claimed
CN-109415601-A Adhesive composition containing reactive silicon sesquioxyalkane 汉高知识产权控股有限责任公司 2019-03-01 CN claimed
EP-3317020-A1 IMPROVED CATALYTIC FAST PYROLYSIS PROCESS WITH IMPURITY REMOVAL Anellotech, Inc. (US) 2018-05-09 EP claimed
CN-107759784-A A kind of preparation method of amine terminated polyether 李晓龙 2018-03-06 CN claimed
CN-107663256-A A kind of polyhydroxy polycarboxylic butadiene and preparation method thereof 陈荣芬 2018-02-06 CN claimed
US-9856424-B2 Integrated hydrocracking process SAUDI BASIC INDUSTRIES CORPORATION (SA) 2018-01-02 US claimed
US-20170204062-A1 PROCESS FOR THE PREPARATION OF REGORAFENIB AND ITS CRYSTALLINE FORMS SHILPA MEDICARE LIMITED (IN) 2017-07-20 US claimed
EP-0242620-B1 MODIFIED PHENOLIC FOAM CATALYSTS AND METHOD FIBERGLAS CANADA Inc. (CA) 1991-06-12 EP claimed
US-4936933-A MIXING, ENTRAINMENT OF GAS BUBBLES IN WATER-IN-OIL EMULSION EXPLOSIVE ICI AUSTRALIA OPERATIONS PROPRIETARY LIMITED (AU) 1990-06-26 US claimed
CN-88105504-A From the useless carclazyte of refined wax, extract the method for paraffin 1988-10-12 CN claimed
US-4707300-A PHENOLIC RESINS MODIFIED WITH MERCAPTAINS THE GOODYEAR TIRE & RUBBER COMPANY (US) 1987-11-17 US claimed
US-4533729-A NONCATALYTIC COPOLYMERIZATION OF POLYHYDRIC ALCOHOLS; CHLOROFORMATE-END GROUP REMOVAL USING TERT-AMINE CATALYST EASTMAN KODAK COMPANY (US) 1985-08-06 US claimed
EP-0105063-A1 Liquid hard-surface cleaner THE PROCTER & GAMBLE COMPANY (US) 1984-04-11 EP claimed
EP-0051363-B1 AN ADHESIVE PRIMER COMPOSITION Toray Silicone Co., Ltd. (JP) 1984-04-04 EP claimed
US-4360422-A ADDING A MIXTURE OF HEAVY AND LIGHT MINERAL OILS TO AN AQUEOUS SLURRY; HEATING, DEASHINGF HIGH STRENGTH IDEMITSU KOSAN CO., LTD. (JP) 1982-11-23 US claimed
US-4046641-A Process and apparatus for the separation of crude benzol and naphthalene from washing oil DR. C. OTTO & COMP. G.M.B.H. (DT) 1977-09-06 US claimed
US-4009232-A Method for the production of carbon microspheres 1-20 μ in diameter KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JA) 1977-02-22 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170204062-A1 PROCESS FOR THE PREPARATION OF REGORAFENIB AND ITS CRYSTALLINE FORMS BRAF, ALK, NRAS ACHE 4229/4885TSHR 3269/4885LMNA 3428/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.