Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.52 |
| ▸ | CA12 | O43570 | 11/20 | 0.47 |
| ▸ | CA1 | P00915 | 11/20 | 0.47 |
| ▸ | CA2 | P00918 | 11/20 | 0.47 |
| ▸ | CA9 | Q16790 | 11/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | IDE | P14735 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HLCS | P50747 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4455260 | 0.80 | TDP1 (0.55) | TDP1CA12CA1CA2CA9 | |
| SCHEMBL179912 | 0.80 | TDP1 (0.55) | TDP1CA12CA1CA2CA9 | |
| SCHEMBL12569327 | 0.80 | TDP1 (0.55) | TDP1CA12CA1CA2CA9 | |
| SCHEMBL18780618 | 0.80 | TDP1 (0.55) | TDP1CA12CA1CA2CA9 | |
| SCHEMBL6033324 | 0.80 | TDP1 (0.55) | TDP1CA12CA1CA2CA9 | |
| SCHEMBL14417100 | 0.80 | TDP1 (0.55) | TDP1CA12CA1CA2CA9 | |
| SCHEMBL17385535 | 0.79 | TDP1 (0.58) | TDP1CA12CA1CA2CA9 | |
| SCHEMBL14417216 | 0.79 | TDP1 (0.58) | TDP1CA12CA1CA2CA9 | |
| SCHEMBL1979297 | 0.79 | TDP1 (0.58) | TDP1CA12CA1CA2CA9 | |
| SCHEMBL3622089 | 0.79 | TDP1 (0.54) | TDP1CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7534819-B2 | Compositions and methods for intracellular delivery of biotinylated cargo | UNIVERSITY OF WASHINGTON (US) | 2009-05-19 | — | — | US | disclosed |
| US-20060281677-A1 | Compositions and methods for intracellular delivery of biotinylated cargo | UNIVERSITY OF WASHINGTON (US) | 2006-12-14 | — | — | US | disclosed |