Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 11/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.55 |
| ▸ | ACHE | P22303 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | GBA1 | P04062 | 1/20 | 0.52 |
| ▸ | CKS1B | P61024 | 2/20 | 0.51 |
| ▸ | SKP1 | P63208 | 2/20 | 0.51 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.51 |
| ▸ | SMO | Q99835 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12964579 | 0.81 | GPR119 (0.77) | GPR119MAPTACHEPOLBCKS1B | |
| SCHEMBL24970948 | 0.79 | POLB (0.55) | GPR119ACHEPOLBGBA1CKS1B | |
| SCHEMBL30903372 | 0.79 | POLB (0.55) | GPR119ACHEPOLBGBA1CKS1B | |
| SCHEMBL5369080 | 0.79 | POLB (0.54) | GPR119ACHEPOLBGBA1CKS1B | |
| SCHEMBL16249699 | 0.78 | PTPN11 (0.52) | GPR119MAPTPTPN11ACHECKS1B | |
| SCHEMBL4063357 | 0.77 | CKS1B (0.69) | GPR119MAPTPTPN11ACHEGBA1 | |
| SCHEMBL6786128 | 0.77 | GPR119 (0.60) | GPR119MAPTPTPN11ACHEPOLB | |
| SCHEMBL2420167 | 0.77 | POLB (0.52) | GPR119MAPTACHEPOLBGBA1 | |
| SCHEMBL2419663 | 0.77 | POLB (0.52) | GPR119MAPTACHEPOLBGBA1 | |
| SCHEMBL6645424 | 0.77 | GPR119 (0.57) | GPR119MAPTPTPN11ACHEPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090264415-A2 | PYRIDO(3,2-D)PYRIMIDINES AND PHARMACEUTICAL COMPOSITIONS USEFUL FOR MEDICAL TREATMENT | 4 AZA IP NV (BE) | 2009-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090264415-A2 | PYRIDO(3,2-D)PYRIMIDINES AND PHARMACEUTICAL COMPOSITIONS USEFUL FOR MEDICAL TREATMENT | PNPO, TYMP, PNP | GPR119 1724/4885MAPT 1541/4885PTPN11 1566/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.