Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR3 | P49682 | 2/20 | 0.44 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.39 |
| ▸ | XDH | P47989 | 2/20 | 0.38 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HPGDS | O60760 | 1/20 | 0.33 |
| ▸ | MLYCD | O95822 | 1/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4109478 | 0.82 | XDH (0.44) | CXCR3XDHFTOSMN1; SMN2MAPT | |
| SCHEMBL4508778 | 0.79 | NPY2R (0.38) | CXCR3SLC6A7LMNAMAPTP2RY12 | |
| SCHEMBL16496558 | 0.77 | GRM1 (0.34) | SLC6A7 | |
| SCHEMBL4508825 | 0.76 | GRM4 (0.42) | CXCR3SLC6A7SMN1; SMN2LMNA | |
| SCHEMBL4106693 | 0.76 | NR1H2 (0.49) | CXCR3 | |
| SCHEMBL4499790 | 0.76 | P2RY12 (0.47) | CXCR3SLC6A7P2RY12 | |
| SCHEMBL15992798 | 0.76 | SMN1; SMN2 (0.36) | SLC6A7SMN1; SMN2LMNAKDM4CMAPT | |
| SCHEMBL15992614 | 0.75 | TRPV1 (0.40) | CXCR3SLC6A7SMN1; SMN2LMNAP2RY12 | |
| Trifluoroacetic Acid SCHEMBL4514310 | 0.73 | SLC2A1 (0.35) | CXCR3SMN1; SMN2LMNA | |
| SCHEMBL5599292 | 0.73 | NR1H2 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090042852-A1 | Novel Pyridine Compounds | ASTRAZENECA AB (SE) | 2009-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090042852-A1 | Novel Pyridine Compounds | P2RY12, P2RY11, P2RY1 | CXCR3 962/4885SLC6A7 3880/4885XDH 425/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.