Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.47 |
| ▸ | PPARG | P37231 | 7/20 | 0.47 |
| ▸ | PPARD | Q03181 | 7/20 | 0.47 |
| ▸ | PPARA | Q07869 | 7/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.47 |
| ▸ | TSHR | P16473 | 5/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TLR2 | O60603 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | FABP4 | P15090 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.47 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.47 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | PDE4A | P27815 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4522861 | 1.00 | GPR84 (0.47) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL4528638 | 0.92 | AKR1B1 (0.41) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL591509 | 0.87 | FFAR4 (0.54) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL11316958 | 0.87 | FFAR4 (0.54) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL11214875 | 0.84 | GPR84 (0.45) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL27123769 | 0.83 | FFAR4 (0.57) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL2504161 | 0.81 | TSHR (0.48) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL14809951 | 0.81 | TSHR (0.48) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL14809356 | 0.81 | TSHR (0.48) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL14809615 | 0.81 | TSHR (0.48) | GPR84PPARGPPARDPPARAHDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8623795-B2 | Method for maintaining antiwear performance of turbine oils containing polymerized amine antioxidants and for improving the deposit formation resistance performance of turbine oils containing monomeric and/or polymeric antioxidants | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2014-01-07 | — | — | US | disclosed |
| US-20130040867-A1 | TRUNK PISTON ENGINE LUBRICATING OIL COMPOSITIONS | CHEVRON ORONITE TECHNOLOGY B.V. (US) | 2013-02-14 | — | — | US | disclosed |
| US-8318643-B2 | Trunk piston engine lubricating oil compositions | Cherron Oronite Technology B.V. (NL) | 2012-11-27 | — | — | US | disclosed |
| US-8207098-B2 | Lubricant additive, lubricant composition and grease composition | YAMANASHI UNIVERSITY (JP) | 2012-06-26 | — | — | US | disclosed |
| US-20120142567-A1 | METHOD FOR MAINTAINING ANTIWEAR PERFORMANCE OF TURBINE OILS CONTAINING POLYMERIZED AMINE ANTIOXIDANTS AND FOR IMPROVING THE DEPOSIT FORMATION RESISTANCE PERFORMANCE OF TURBINE OILS CONTAINING MONOMERIC AND/OR POLYMERIC ANTIOXIDANTS | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2012-06-07 | — | — | US | disclosed |
| US-20110319304-A1 | Trunk piston engine lubricating oil compositions | CHEVRON ORONITE TECHNOLOGY B.V. (NL) | 2011-12-29 | — | — | US | disclosed |
| US-20090239773-A1 | LUBRICANT ADDITIVE, LUBRICANT COMPOSITION AND GREASE COMPOSITION | YAMANASHI UNIVERSITY (JP) | 2009-09-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090239773-A1 | LUBRICANT ADDITIVE, LUBRICANT COMPOSITION AND GREASE COMPOSITION | GRN, GRIA1, GRIK5 | GPR84 1757/4885PPARG 790/4885PPARD 1260/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.