Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Benzophenone. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.93 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.74 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.74 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.74 |
| ▸ | ATM | Q13315 | 1/20 | 0.74 |
| ▸ | MEN1 | O00255 | 3/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | CES2 | O00748 | 2/20 | 0.61 |
| ▸ | CES1 | P23141 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | DAO | P14920 | 1/20 | 0.61 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.61 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.61 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.61 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.61 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzophenone SCHEMBL665150 | 1.00 | ALDH1A1 (0.93) | ALDH1A1SRD5A2TDP1L3MBTL1ATM | |
| Benzophenone SCHEMBL377243 | 1.00 | ALDH1A1 (0.93) | ALDH1A1SRD5A2TDP1L3MBTL1ATM | |
| Benzophenone SCHEMBL28180817 | 0.97 | ALDH1A1 (1.00) | ALDH1A1SRD5A2TDP1L3MBTL1ATM | |
| Benzophenone SCHEMBL30537001 | 0.97 | ALDH1A1 (1.00) | ALDH1A1SRD5A2TDP1L3MBTL1ATM | |
| Benzophenone SCHEMBL17745 | 0.97 | ALDH1A1 (1.00) | ALDH1A1SRD5A2TDP1L3MBTL1ATM | |
| Benzophenone SCHEMBL1074283 | 0.97 | ALDH1A1 (1.00) | ALDH1A1SRD5A2TDP1L3MBTL1ATM | |
| Benzophenone SCHEMBL28491203 | 0.97 | ALDH1A1 (1.00) | ALDH1A1SRD5A2TDP1L3MBTL1ATM | |
| Benzophenone SCHEMBL6061130 | 0.97 | ALDH1A1 (1.00) | ALDH1A1SRD5A2TDP1L3MBTL1ATM | |
| Benzophenone SCHEMBL30536983 | 0.97 | ALDH1A1 (1.00) | ALDH1A1SRD5A2TDP1L3MBTL1ATM | |
| Benzophenone SCHEMBL23175179 | 0.93 | ALDH1A1 (0.93) | ALDH1A1SRD5A2TDP1L3MBTL1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2765150-B1 | Resin composition for manufacturing thermoplastic polyester resin by using green catalyst | LOTTE CHEMICAL CORP (KR) | 2017-11-15 | — | — | EP | claimed |
| US-20090069472-A1 | ANTISTATIC AGENTS FOR RESINS, ANTISTATIC RESIN COMPOSITIONS, AND ANTISTATIC RESIN MOLDED PRODUCTS | NIPPON CHEMICAL INDUSTRIAL CO., LTD. (JP) | 2009-03-12 | — | — | US | disclosed |
| EP-1574548-B1 | ANTISTATIC AGENTS FOR RESINS, ANTISTATIC RESIN COMPOSITIONS, AND MOLDINGS OF ANTISTATIC RESINS | NIPPON CHEMICAL IND (JP) | 2008-04-16 | — | — | EP | disclosed |
| US-20060100326-A1 | Antistatic agents for resins, antistatic resin compositions, and molding of antistatic resins | NIPPPON CHEMICAL INDUSTRIAL CO., LTD (JP) | 2006-05-11 | — | — | US | disclosed |
| EP-1574548-A1 | ANTISTATIC AGENTS FOR RESINS, ANTISTATIC RESIN COMPOSITIONS, AND MOLDINGS OF ANTISTATIC RESINS | Nippon Chemical Industrial Co., Ltd. (JP) | 2005-09-14 | — | — | EP | disclosed |
| EP-0625998-A1 | RADIATION CROSSLINKED ELASTOMERS. | MINNESOTA MINING & MFG (US) | 1994-11-30 | — | — | EP | disclosed |
| WO-1993016131-A1 | RADIATION CROSSLINKED ELASTOMERS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1993-08-19 | — | — | WO | disclosed |
| EP-0124741-B1 | PROCESS FOR THE PRODUCTION OF POLYAMIDE-POLYESTER BLOCK POLYMERS | BAYER AG (DE) | 1987-01-28 | — | — | EP | disclosed |
| EP-0124741-A1 | Process for the production of polyamide-polyester block polymers | BAYER AG (DE) | 1984-11-14 | — | — | EP | disclosed |