Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PADI4 | Q9UM07 | 2/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.43 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.43 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8237568 | 0.95 | ALOX5 (0.47) | PADI4ALOX5 | |
| SCHEMBL13605640 | 0.95 | ALOX5 (0.49) | PADI4ALOX5 | |
| SCHEMBL13605644 | 0.88 | PADI4 (0.44) | PADI4 | |
| SCHEMBL13605639 | 0.87 | PADI4 (0.49) | PADI4 | |
| SCHEMBL13605645 | 0.85 | PADI4 (0.54) | PADI4 | |
| SCHEMBL13605642 | 0.84 | PADI4 (0.48) | PADI4 | |
| SCHEMBL4533208 | 0.81 | KDM4E (0.49) | — | |
| Hydrochloric Acid SCHEMBL4520231 | 0.80 | KDM4E (0.48) | — | |
| SCHEMBL4523027 | 0.79 | TNFRSF1A (0.43) | PADI4TNFRSF1A | |
| SCHEMBL8239980 | 0.77 | IKBKB (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090326001-A1 | THIENOPYRIDINE DERIVATIVES AS MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS | RICHTER GEDEON NYRT. (HU) | 2009-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090326001-A1 | THIENOPYRIDINE DERIVATIVES AS MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS | GRM5, GRM1, GRIK5 | PADI4 4808/4885ALOX5 521/4885TNFRSF1A 1959/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.