Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.66 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.66 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.46 |
| ▸ | PPARA | Q07869 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | DRD4 | P21917 | 2/20 | 0.42 |
| ▸ | DRD3 | P35462 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4517044 | 0.84 | LTA4H (0.72) | LTA4HEPHX2FFAR1ALDH1A1RECQL | |
| SCHEMBL13932991 | 0.84 | LTA4H (0.72) | LTA4HEPHX2FFAR1ALDH1A1RECQL | |
| SCHEMBL4523232 | 0.83 | LTA4H (0.45) | LTA4HEPHX2FFAR1DRD2DRD4 | |
| SCHEMBL14463874 | 0.81 | LTA4H (0.77) | LTA4HEPHX2FFAR1ALDH1A1RECQL | |
| SCHEMBL18240129 | 0.80 | LTA4H (0.66) | LTA4HEPHX2FFAR1PPARAALDH1A1 | |
| SCHEMBL4519292 | 0.79 | LTA4H (0.65) | LTA4HEPHX2FFAR1ALDH1A1RECQL | |
| SCHEMBL28142985 | 0.79 | LTA4H (0.56) | LTA4HEPHX2FFAR1PPARAALDH1A1 | |
| SCHEMBL1563277 | 0.79 | LTA4H (1.00) | LTA4HEPHX2FFAR1FFAR4BCHE | |
| SCHEMBL11687518 | 0.78 | LTA4H (0.97) | LTA4HEPHX2FFAR1FFAR4BCHE | |
| SCHEMBL4659369 | 0.78 | LTA4H (0.73) | LTA4HEPHX2FFAR1ALDH1A1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7498460-B2 | Isophthalic acid derivatives | BAYER HEALTHCARE AG (DE) | 2009-03-03 | — | — | US | disclosed |
| US-7498460-B2 | Isophthalic acid derivatives | BAYER HEALTHCARE AG (DE) | 2009-03-03 | — | — | US | disclosed |
| US-20060154912-A1 | Isophtalic acid derivatives | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2006-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060154912-A1 | Isophtalic acid derivatives | VHL, FABP3, CPT1A | LTA4H 281/4885EPHX2 214/4885FFAR1 832/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.