Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 3/20 | 0.31 |
| ▸ | CA2 | P00918 | 3/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3293809 | 0.82 | CYP3A4 (0.32) | TDP1MAOAMAOBMEN1GAA | |
| SCHEMBL3288058 | 0.80 | TDP1 (0.31) | TDP1MEN1GAAKMT2A | |
| SCHEMBL3289724 | 0.78 | TDP1 (0.44) | TDP1MAOAMAOBMEN1GAA | |
| SCHEMBL3289322 | 0.75 | CYP3A4 (0.32) | TDP1MAOAMAOBMEN1GAA | |
| SCHEMBL3290477 | 0.74 | CA1 (0.33) | TDP1MEN1GAAKMT2ACA1 | |
| SCHEMBL7092307 | 0.68 | TDP1 (0.53) | TDP1MAOAMAOBMEN1GAA | |
| SCHEMBL7096250 | 0.68 | TDP1 (0.53) | TDP1MAOAMAOBMEN1GAA | |
| SCHEMBL220281 | 0.68 | TDP1 (0.71) | TDP1MAOAMAOBMEN1GAA | |
| SCHEMBL146037 | 0.68 | TDP1 (0.71) | TDP1MAOAMAOBMEN1GAA | |
| SCHEMBL5866373 | 0.68 | TDP1 (0.71) | TDP1MAOAMAOBMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7531676-B2 | Lipids | CELLTECH R & D LIMITED (GB) | 2009-05-12 | — | — | US | disclosed |