SCHEMBL452393

SCHEMBL452393

[C]1OCCO1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1870256 0.80
SCHEMBL4454206 0.67
SCHEMBL449059 0.59
Fluoride SCHEMBL28271072 0.47
Fluoride SCHEMBL21074152 0.47
Fluoride SCHEMBL27668851 0.47
Fluoride SCHEMBL3793483 0.47
Fluoride SCHEMBL31441110 0.47
Fluoride SCHEMBL29093769 0.47
Oxirane SCHEMBL8094696 0.45 TTR (0.83)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 307 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118076602-A Heteroaryl-acetylenes, pharmaceutical compositions thereof and their therapeutic uses 嘉兴优博生物技术有限公司 2024-05-24 CN claimed
EP-4021904-B1 ALPHA-D-GALACTOPYRANOSIDE DERIVATIVES IDORSIA PHARMACEUTICALS LTD (CH) 2024-01-03 EP claimed
CN-116925171-A Cyclopropylmethyl steroid quaternary ammonium salt-containing compound, intermediate, preparation method and application thereof 时森海(杭州)医药科技有限公司 2023-10-24 CN claimed
EP-4021904-A1 ALPHA-D-GALACTOPYRANOSIDE DERIVATIVES Idorsia Pharmaceuticals Ltd (CH) 2022-07-06 EP claimed
CN-114585619-A alpha-D-galactopyranoside derivatives 爱杜西亚药品有限公司 2022-06-03 CN claimed
WO-2022011274-A1 SUBSTITUTED 1,6-NAPHTHYRIDINE INHIBITORS OF CDK5 GOLDFINCH BIO, INC. (US) 2022-01-13 WO claimed
WO-2021038068-A1 ALPHA-D-GALACTOPYRANOSIDE DERIVATIVES IDORSIA PHARMACEUTICALS LTD (CH) 2021-03-04 WO claimed
US-9828548-B2 Liquid-crystal composition DIC CORPORATION (JP) 2017-11-28 US claimed
US-20150259600-A1 LIQUID-CRYSTAL COMPOSITION DIC CORPORATION (JP) 2015-09-17 US claimed
EP-2860236-A1 LIQUID-CRYSTAL COMPOSITION DIC Corporation (JP) 2015-04-15 EP claimed
US-4889946-A Phenoxybenzoic acid compounds and herbicidal and plant growth regulant compositions BAYER AKTIENGESELLSCHAFT (DE) 1989-12-26 US claimed
EP-0309043-A2 Novel substituted N-(1-alkyl-3-hydroxy-4-piperidinyl)benzamides JANSSEN PHARMACEUTICA N.V. (BE) 1989-03-29 EP claimed
EP-0195496-A2 Use of xanthines in the treatment of proliferative skin disease BEECHAM GROUP PLC (GB) 1986-09-24 EP claimed
EP-0018135-B1 XANTHINE DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND THEIR USE IN PHARMACEUTICAL COMPOSITIONS BEECHAM - WUELFING GmbH &amp; Co. KG (DE) 1983-09-28 EP claimed
EP-0017478-B1 DIALKOXY- AND DIOXACYCLOALKYL-ALKYLTHEOBROMINES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR PREPARATION BEECHAM - WUELFING GmbH &amp; Co. KG (DE) 1983-03-30 EP claimed
EP-0018497-B1 AZOLYLOXY-ACETAMIDES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES BAYER AG (DE) 1982-04-28 EP claimed
EP-0018135-A1 Xanthine derivatives, a process for their preparation and their use in pharmaceutical compositions BEECHAM - WUELFING GmbH &amp; Co. KG (DE) 1980-10-29 EP claimed
EP-0017478-A1 Dialkoxy- and dioxacycloalkyl-alkyltheobromines, pharmaceutical compositions containing them and their preparation BEECHAM - WUELFING GmbH &amp; Co. KG (DE) 1980-10-15 EP claimed
US-4209444-A INHIBITORS OF AGGREGATION OR ADHESION OF THROMBOCYTES MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1980-06-24 US claimed
US-3958003-A HETEROCYCLIC COMPOUND, ANALGESICS CENTRAL NERVOUS SYSTEM DEPRESSANT SANDOZ LTD. (CH) 1976-05-18 US claimed