Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2RL3 | Q96RI0 | 19/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15013253 | 0.81 | SMN1; SMN2 (0.49) | F2RL3CA12CA1CA2CA9 | |
| SCHEMBL1650295 | 0.75 | F2RL3 (0.44) | F2RL3 | |
| SCHEMBL452295 | 0.74 | F2RL3 (0.46) | F2RL3 | |
| SCHEMBL452503 | 0.72 | F2RL3 (0.42) | F2RL3 | |
| SCHEMBL31167885 | 0.67 | F2RL3 (0.41) | F2RL3 | |
| SCHEMBL19434320 | 0.65 | TP53 (0.51) | F2RL3CA12CA1CA2CA9 | |
| SCHEMBL19291869 | 0.64 | TPH1 (0.31) | — | |
| SCHEMBL3400110 | 0.61 | SMN1; SMN2 (0.41) | — | |
| SCHEMBL19306633 | 0.61 | TP53 (0.55) | F2RL3CA12CA1CA2CA9 | |
| SCHEMBL453907 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011121317-A9 | IMIDAZOTHIADIAZOLES FOR USE AS KINASE INHIBITORS | CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS (CNIO) (ES) | 2012-03-15 | — | — | WO | disclosed |
| WO-2011121317-A1 | IMIDAZO [2,1-B] [1,3,4] THIADIAZOLES AS PROTEIN OR LIPID KINASE INHIBITORS | CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS (CNIO) (ES) | 2011-10-06 | — | — | WO | disclosed |