Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 10/20 | 0.40 |
| ▸ | SSTR4 | P31391 | 4/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | REN | P00797 | 6/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11244759 | 0.98 | CTSC (0.39) | CTSCSSTR4KCNH2REN | |
| SCHEMBL7310959 | 0.82 | SSTR4 (0.42) | CTSCSSTR4KCNH2REN | |
| SCHEMBL295081 | 0.77 | SSTR4 (0.44) | CTSCSSTR4REN | |
| SCHEMBL1194327 | 0.77 | SSTR4 (0.41) | CTSCSSTR4REN | |
| SCHEMBL3364696 | 0.77 | SSTR4 (0.41) | CTSCSSTR4REN | |
| SCHEMBL23230712 | 0.77 | SSTR4 (0.44) | CTSCSSTR4REN | |
| SCHEMBL2688364 | 0.77 | SSTR4 (0.41) | CTSCSSTR4REN | |
| SCHEMBL294851 | 0.77 | SSTR4 (0.41) | CTSCSSTR4REN | |
| SCHEMBL15485217 | 0.74 | NOS2 (0.41) | — | |
| SCHEMBL9204612 | 0.74 | SSTR4 (0.46) | CTSCSSTR4REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102690280-B | Chiral zinc nitrogen coordination compounds | LUO MEI | 2015-02-11 | — | — | CN | disclosed |
| CN-102690280-A | Chiral zinc nitrogen coordination compounds | MEI LUO | 2012-09-26 | — | — | CN | disclosed |
| US-20090030197-A1 | Quinoline Intermediates of Receptor Tyrosine Kinase Inhibitors and the Synthesis Thereof | WYETH (US) | 2009-01-29 | — | — | US | disclosed |
| US-7432377-B2 | Quinoline intermediates of receptor tyrosine kinase inhibitors and the synthesis thereof | WYETH (US) | 2008-10-07 | — | — | US | disclosed |
| EP-1711467-A2 | QUINOLINE INTERMEDIATES OF RECEPTOR TYROSINE KINASE INHIBITORS AND THE SYNTHESIS THEREOF | Wyeth (US) | 2006-10-18 | — | — | EP | disclosed |
| WO-2005070890-A2 | QUINOLINE INTERMEDIATES OF RECEPTOR TYROSINE KINASE INHIBITORS AND THE SYNTHESIS THEREOF | WYETH (US) | 2005-08-04 | — | — | WO | disclosed |
| US-20050159446-A1 | Quinoline intermediates of receptor tyrosine kinase inhibitors and the synthesis thereof | WYETH | 2005-07-21 | — | — | US | disclosed |
| EP-0008802-B1 | ERGOLINE DERIVATIVES, THEIR PREPARATION AND THERAPEUTIC COMPOSITION CONTAINING THEM | FARMITALIA CARLO ERBA S.p.A. (IT) | 1982-07-21 | — | — | EP | disclosed |
| US-4321381-A | Ergot derivatives | FARMITALIA CARLO ERBA S.P.A. (IT) | 1982-03-23 | — | — | US | disclosed |
| US-4252941-A | HYPOTENSIVE AGENTS, ANTIPROLACTINIC AGENTS | FARMITALIA CARLO ERBA S.P.A. (IT) | 1981-02-24 | — | — | US | disclosed |
| EP-0008802-A1 | Ergoline derivatives, their preparation and therapeutic composition containing them | FARMITALIA CARLO ERBA S.p.A. (IT) | 1980-03-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090030197-A1 | Quinoline Intermediates of Receptor Tyrosine Kinase Inhibitors and the Synthesis Thereof | ABL1, RET, ERBB2 | CTSC 2499/4885SSTR4 1118/4885KCNH2 1930/4885 |
| US-20050159446-A1 | Quinoline intermediates of receptor tyrosine kinase inhibitors and the synthesis thereof | ABL1, RET, ERBB2 | CTSC 2499/4885SSTR4 1118/4885KCNH2 1930/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.