Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 12/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 12/20 | 0.59 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 9/20 | 0.57 |
| ▸ | ACP1 | P24666 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | EGFR | P00533 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.50 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.50 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4525147 | 1.00 | MEN1 (0.59) | MEN1KMT2ARXFP1MAPTACP1 | |
| SCHEMBL4525152 | 1.00 | MEN1 (0.59) | MEN1KMT2ARXFP1MAPTACP1 | |
| SCHEMBL4506193 | 0.85 | MEN1 (0.60) | MEN1KMT2ARXFP1MAPTACP1 | |
| SCHEMBL4506204 | 0.85 | MEN1 (0.60) | MEN1KMT2ARXFP1MAPTACP1 | |
| SCHEMBL4506199 | 0.85 | MEN1 (0.60) | MEN1KMT2ARXFP1MAPTACP1 | |
| SCHEMBL4519709 | 0.83 | MEN1 (0.58) | MEN1KMT2ARXFP1MAPTACP1 | |
| SCHEMBL4519713 | 0.83 | MEN1 (0.58) | MEN1KMT2ARXFP1MAPTACP1 | |
| SCHEMBL4519715 | 0.83 | MEN1 (0.58) | MEN1KMT2ARXFP1MAPTACP1 | |
| SCHEMBL3907257 | 0.82 | MEN1 (0.65) | MEN1KMT2ARXFP1MAPTACP1 | |
| SCHEMBL4501723 | 0.82 | MEN1 (0.65) | MEN1KMT2ARXFP1MAPTACP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090247519-A1 | AMINO-ETHYL-AMINO-ARYL (AEAA) COMPOUNDS AND THEIR USE | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2009-10-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090247519-A1 | AMINO-ETHYL-AMINO-ARYL (AEAA) COMPOUNDS AND THEIR USE | PKD2, PKD1, AADAT | MEN1 4237/4885KMT2A 230/4885RXFP1 3771/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.