Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 5/20 | 0.50 |
| ▸ | NT5E | P21589 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31126649 | 1.00 | TDP1 (1.00) | TDP1ALDH1A1LMNATSHRNT5E | |
| SCHEMBL25711 | 1.00 | TDP1 (1.00) | TDP1ALDH1A1LMNATSHRNT5E | |
| SCHEMBL331672 | 0.98 | TDP1 (0.95) | TDP1ALDH1A1LMNATSHRNT5E | |
| SCHEMBL813503 | 0.98 | TDP1 (0.95) | TDP1ALDH1A1LMNATSHRNT5E | |
| SCHEMBL94888 | 0.98 | TDP1 (0.95) | TDP1ALDH1A1LMNATSHRNT5E | |
| SCHEMBL2121269 | 0.98 | TDP1 (0.95) | TDP1ALDH1A1LMNATSHRNT5E | |
| Hydrochloric Acid SCHEMBL8527191 | 0.98 | TDP1 (0.95) | TDP1ALDH1A1LMNATSHRNT5E | |
| SCHEMBL2198423 | 0.98 | TDP1 (0.95) | TDP1ALDH1A1LMNATSHRNT5E | |
| SCHEMBL17476641 | 0.98 | TDP1 (0.95) | TDP1ALDH1A1LMNATSHRNT5E | |
| Ammonia Solution, Strong SCHEMBL814454 | 0.98 | TDP1 (0.95) | TDP1ALDH1A1LMNATSHRNT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120061608-A1 | FUNCTIONAL PARTICLE WITH ROUGH-SURFACED POLYMER COATING | HITACHI MAXELL, LTD. (JP) | 2012-03-15 | — | — | US | disclosed |