⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL198099 | 0.91 | — | — | |
| SCHEMBL1973 | 0.72 | MAPT (0.36) | — | |
| SCHEMBL25470 | 0.72 | KDM4E (0.32) | — | |
| SCHEMBL452574 | 0.68 | — | — | |
| SCHEMBL449631 | 0.68 | — | — | |
| SCHEMBL3626687 | 0.67 | — | — | |
| SCHEMBL3626719 | 0.67 | — | — | |
| SCHEMBL3831708 | 0.67 | — | — | |
| SCHEMBL451496 | 0.67 | — | — | |
| SCHEMBL196535 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5512209-A | IMPROVED RESPONSE CHARACTERISTICS AND HIGH CONTRAST; DISPOSING COMPOSITION BETWEEN ELECTRODE PLATES | CANON KABUSHIKI KAISHA (JP) | 1996-04-30 | — | — | US | claimed |
| EP-0622359-A1 | Quinoxaline compound, liquid crystal composition containing the compound, liquid crystal device using the composition, display apparatus and display method | CANON KABUSHIKI KAISHA (JP) | 1994-11-02 | — | — | EP | claimed |
| US-20150216861-A1 | CYCLOPROPYL AMIDE DERIVATIVES | ASTRAZENECA AB (SE) | 2015-08-06 | — | — | US | disclosed |
| US-9029381-B2 | Cyclopropyl amide derivatives | ASTRAZENECA AB (SE) | 2015-05-12 | — | — | US | disclosed |
| EP-2805937-A1 | Cyclopropyl amide derivatives | AstraZeneca AB (SE) | 2014-11-26 | — | — | EP | disclosed |
| EP-2253615-B1 | Cyclopropyl amide derivatives | ASTRAZENECA AB (SE) | 2014-07-09 | — | — | EP | disclosed |
| EP-2195293-B1 | CYCLOPTOPYL AMIDE DERIVATIVES | ASTRAZENECA AB (SE) | 2013-10-16 | — | — | EP | disclosed |
| US-20120065193-A1 | Cyclopropyl Amide Derivatives '978 | ASTRAZENECA AB (SE) | 2012-03-15 | — | — | US | disclosed |
| US-8063215-B2 | Cyclopropyl amide derivatives | ASTRAZENECA AB (SE) | 2011-11-22 | — | — | US | disclosed |
| WO-2011105700-A1 | NOVEL ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME | ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) | 2011-09-01 | — | — | WO | disclosed |
| EP-2253615-A1 | Cyclopropyl amide derivatives | AstraZeneca AB (SE) | 2010-11-24 | — | — | EP | disclosed |
| US-20100130477-A1 | Spirocyclobutyl Piperidine Derivatives | ASTRAZENECA AB (SE) | 2010-05-27 | — | — | US | disclosed |
| US-7566781-B2 | Imidazopyridine compound | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2009-07-28 | — | — | US | disclosed |
| US-20090076020-A1 | Cyclopropyl Amide Derivatives 978 | ASTRAZENECA AB (SE) | 2009-03-19 | — | — | US | disclosed |
| WO-2009024823-A2 | OXADIAZOLE DERIVATIVES AS DGAT INHIBITORS | ASTRAZENECA AB (SE) | 2009-02-26 | — | — | WO | disclosed |
| US-20070249659-A1 | melanin concentrating hormone receptor antagonist; preventing or treating vascular system diseases, nervous system disorders, metabolic disorders, urogenital diseases, respiratory diseases disorders; N-(2-ethyl-3-methylimidazo[1,2-a]pyridin-6-yl)-3-fluoro-4-(pyridin-2-ylmethoxy)benzamide | BANYU PHARMACEUTICAL., LTD. (JP) | 2007-10-25 | — | — | US | disclosed |
| EP-1748048-A1 | IMIDAZOPYRIDINE COMPOUND | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2007-01-31 | — | — | EP | disclosed |
| EP-0622359-B1 | Quinoxaline compound, liquid crystal composition containing the compound, liquid crystal device using the composition, display apparatus and display method | CANON KK (JP) | 2003-03-19 | — | — | EP | disclosed |
| US-5512209-A | IMPROVED RESPONSE CHARACTERISTICS AND HIGH CONTRAST; DISPOSING COMPOSITION BETWEEN ELECTRODE PLATES | CANON KABUSHIKI KAISHA (JP) | 1996-04-30 | — | — | US | disclosed |
| EP-0622359-A1 | Quinoxaline compound, liquid crystal composition containing the compound, liquid crystal device using the composition, display apparatus and display method | CANON KABUSHIKI KAISHA (JP) | 1994-11-02 | — | — | EP | disclosed |