⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL196535 | 0.84 | — | — | |
| SCHEMBL2910 | 0.73 | CYP1A2 (0.44) | — | |
| SCHEMBL4315969 | 0.71 | — | — | |
| SCHEMBL9322559 | 0.70 | ACHE (0.42) | — | |
| SCHEMBL1450761 | 0.70 | CYP1A2 (0.52) | — | |
| SCHEMBL6360076 | 0.69 | — | — | |
| SCHEMBL198099 | 0.68 | — | — | |
| SCHEMBL452557 | 0.68 | — | — | |
| SCHEMBL16316 | 0.68 | MAP4K4 (0.34) | — | |
| SCHEMBL4843118 | 0.68 | BACE1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230210840-A1 | BACTERIAL NITRIC OXIDE SYNTHASE INHIBITORS | NORTHWESTERN UNIVERSITY | 2023-07-06 | — | — | US | disclosed |
| CN-114805831-A | Metal organic material and preparation method | 耶达研究及发展有限公司 | 2022-07-29 | — | — | CN | disclosed |
| CN-113166098-A | Triazine compound, material for organic electroluminescent element, and organic electroluminescent element | 东曹株式会社 | 2021-07-23 | — | — | CN | disclosed |
| US-9707540-B2 | Metal-organic materials and method for preparation | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2017-07-18 | — | — | US | disclosed |
| US-9611218-B2 | Metal-organic materials and method for preparation | YEDA RESEARCH AND DEVELOPMENT CO., LTD. (IL) | 2017-04-04 | — | — | US | disclosed |
| US-20160271582-A1 | METAL-ORGANIC MATERIALS AND METHOD FOR PREPARATION | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2016-09-22 | — | — | US | disclosed |
| CN-105873987-A | Metal organic material and preparation method | 耶达研究及发展有限公司 | 2016-08-17 | — | — | CN | disclosed |
| US-20160152568-A1 | METAL-ORGANIC MATERIALS AND METHOD FOR PREPARATION | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2016-06-02 | — | — | US | disclosed |
| EP-3022250-A1 | METAL-ORGANIC MATERIALS AND METHOD FOR PREPARATION | YEDA RESEARCH AND DEVELOPMENT CO. LTD., AT THE WEI (IL) | 2016-05-25 | — | — | EP | disclosed |
| US-20150216861-A1 | CYCLOPROPYL AMIDE DERIVATIVES | ASTRAZENECA AB (SE) | 2015-08-06 | — | — | US | disclosed |
| EP-2195293-A2 | CYCLOPTOPYL AMIDE DERIVATIVES | AstraZeneca AB (SE) | 2010-06-16 | — | — | EP | disclosed |
| WO-2010062245-A1 | SPIROCYCLOBUTYL PIPERIDINE DERIVATIVES | ASTRAZENECA AB (SE) | 2010-06-03 | — | — | WO | disclosed |
| US-20100130477-A1 | Spirocyclobutyl Piperidine Derivatives | ASTRAZENECA AB (SE) | 2010-05-27 | — | — | US | disclosed |
| US-20090076020-A1 | Cyclopropyl Amide Derivatives 978 | ASTRAZENECA AB (SE) | 2009-03-19 | — | — | US | disclosed |
| WO-2009024823-A2 | OXADIAZOLE DERIVATIVES AS DGAT INHIBITORS | ASTRAZENECA AB (SE) | 2009-02-26 | — | — | WO | disclosed |
| US-20050085447-A1 | Pyrido[3,4-d]pyrimidine derivatives as matrix metalloproteinase-13 inhibitors | WARNER-LAMBERT COMPANY LLC | 2005-04-21 | — | — | US | disclosed |
| WO-2005016926-A1 | PYRIDO [3,4-D] PYRIMIDINE DERIVATIVES AS MATRIX METALLOPROTEINASE-13 INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2005-02-24 | — | — | WO | disclosed |
| US-6166210-A | Perylene imide monocarboxylic acids | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2000-12-26 | — | — | US | disclosed |
| EP-1053228-A1 | PERYLENE IMIDE MONOCARBOXYLIC ACIDS AS COLORANTS | Ciba SC Holding AG (CH) | 2000-11-22 | — | — | EP | disclosed |
| WO-1999031069-A1 | PERYLENE IMIDE MONOCARBOXYLIC ACIDS AS COLORANTS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 1999-06-24 | — | — | WO | disclosed |