Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP15 | Q460N3 | 4/20 | 0.54 |
| ▸ | PARP10 | Q53GL7 | 4/20 | 0.54 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.54 |
| ▸ | ACACB | O00763 | 3/20 | 0.46 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | UGCG | Q16739 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30932889 | 0.85 | PARP15 (0.51) | PARP15PARP10PARP2ACACBGPR88 | |
| SCHEMBL29024848 | 0.83 | PARP15 (0.64) | PARP15PARP10PARP2TDP1SIGMAR1 | |
| SCHEMBL21910441 | 0.82 | PARP15 (0.49) | PARP15PARP10PARP2ACACBGPR88 | |
| SCHEMBL14033727 | 0.82 | GPR88 (0.54) | PARP15PARP10PARP2GPR88FFAR1 | |
| SCHEMBL10014749 | 0.81 | PARP15 (0.50) | PARP15PARP10PARP2ACACBGPR88 | |
| SCHEMBL7813334 | 0.79 | PARP15 (0.43) | PARP15PARP10PARP2ACACBUGCG | |
| SCHEMBL19876587 | 0.78 | PARP15 (0.51) | PARP15PARP10PARP2ACACBGPR88 | |
| SCHEMBL17246825 | 0.78 | PARP15 (0.51) | PARP15PARP10PARP2ACACBGPR88 | |
| SCHEMBL7601081 | 0.78 | PARP15 (0.51) | PARP15PARP10PARP2ACACBGPR88 | |
| SCHEMBL16902834 | 0.78 | PARP15 (0.59) | PARP15PARP10PARP2TDP1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7498460-B2 | Isophthalic acid derivatives | BAYER HEALTHCARE AG (DE) | 2009-03-03 | — | — | US | disclosed |
| US-20060154912-A1 | Isophtalic acid derivatives | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2006-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060154912-A1 | Isophtalic acid derivatives | VHL, FABP3, CPT1A | PARP15 3998/4885PARP10 4535/4885PARP2 3805/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.