Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.55 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.42 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5209887 | 0.91 | CYSLTR2 (0.56) | CYSLTR2PLA2G4BPOLBCASP6NR1H4 | |
| SCHEMBL4526773 | 0.89 | CYSLTR2 (0.64) | CYSLTR2PLA2G4BPOLBCASP6NR1H4 | |
| SCHEMBL4532981 | 0.87 | CYSLTR2 (0.55) | CYSLTR2PLA2G4BPOLBCASP6NR1H4 | |
| SCHEMBL6199651 | 0.85 | CYSLTR2 (0.59) | CYSLTR2PLA2G4BPOLBCASP6NR1H4 | |
| SCHEMBL4522253 | 0.83 | CYSLTR2 (0.64) | CYSLTR2PLA2G4BPOLBCASP6NR1H4 | |
| SCHEMBL5206606 | 0.83 | CYSLTR2 (0.47) | CYSLTR2FFAR1PDE4APDE4BPDE4C | |
| SCHEMBL13918523 | 0.82 | CYSLTR2 (0.65) | CYSLTR2PLA2G4BMAPTS1PR1S1PR3 | |
| SCHEMBL4516413 | 0.81 | CYSLTR2 (0.56) | CYSLTR2PLA2G4BPOLBCASP6NR1H4 | |
| SCHEMBL13918454 | 0.81 | CYSLTR2 (0.62) | CYSLTR2PLA2G4BPOLBNR1H4FFAR1 | |
| SCHEMBL5211440 | 0.81 | CYSLTR2 (0.50) | CYSLTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1572628-B1 | ISOPHTALIC ACID DERIVATIVES | BAYER HEALTHCARE AG (DE) | 2007-07-25 | — | — | EP | disclosed |