SCHEMBL4527196

SCHEMBL4527196

CC(C)NCC(C)[SiH](O)O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 8/20 0.39
TSHR P16473 2/20 0.39
HIF1A Q16665 2/20 0.39
ADRA1A P35348 2/20 0.39
MEN1 O00255 2/20 0.33
LMNA P02545 2/20 0.33
KMT2A Q03164 2/20 0.33
APEX1 P27695 1/20 0.33
BLM P54132 1/20 0.33
PTGS1 P23219 1/20 0.33
SLC6A2 P23975 1/20 0.33
ADRB1 P08588 6/20 0.31
ADRB3 P13945 4/20 0.31
MAPT P10636 2/20 0.31
MTOR P42345 2/20 0.31
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
HPGD P15428 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4525902 0.74 CYP2D6 (0.32) HIF1ACYP2D6
SCHEMBL9411609 0.67
SCHEMBL438759 0.67
SCHEMBL15509647 0.67 ADRB2 (0.47) ADRB2TSHRHIF1AADRA1APTGS1
SCHEMBL1669422 0.67
SCHEMBL438321 0.67
SCHEMBL9407492 0.65 ADRB2 (0.36) ADRB2TSHRHIF1AADRA1AMEN1
SCHEMBL21788095 0.65 ADRB2 (0.36) ADRB2TSHRHIF1AADRA1AMEN1
SCHEMBL91192 0.65
Hydrochloric Acid SCHEMBL11098954 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7507480-B2 Corrosion-resistant metal surfaces BROOKHAVEN SCIENCE ASSOCIATES, LLC (US) 2009-03-24 US disclosed
US-20060269760-A1 Corrosion-resistant metal surfaces ENERGY, UNITED STATES DEPARTMENT OF 2006-11-30 US disclosed