Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.58 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.55 |
| ▸ | CHRNA7 | P36544 | 12/20 | 0.51 |
| ▸ | CHRNA10 | Q9GZZ6 | 4/20 | 0.50 |
| ▸ | CHRNA9 | Q9UGM1 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.49 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.49 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4527397 | 1.00 | PPARA (0.58) | PPARAKCNA3CHRNA7CHRNA10CHRNA9 | |
| SCHEMBL4508135 | 0.90 | PPARA (0.48) | PPARAKCNA3CHRNA7CHRNA10CHRNA9 | |
| SCHEMBL4508128 | 0.90 | PPARA (0.48) | PPARAKCNA3CHRNA7CHRNA10CHRNA9 | |
| SCHEMBL4508132 | 0.90 | PPARA (0.48) | PPARAKCNA3CHRNA7CHRNA10CHRNA9 | |
| SCHEMBL11827906 | 0.84 | AHR (0.57) | CHRNA7CHRNB4CHRNA3 | |
| SCHEMBL11827899 | 0.84 | AHR (0.57) | CHRNA7CHRNB4CHRNA3 | |
| SCHEMBL10949490 | 0.84 | LTA4H (0.52) | ALDH1A1RECQL | |
| SCHEMBL10949485 | 0.84 | LTA4H (0.52) | ALDH1A1RECQL | |
| SCHEMBL11828016 | 0.83 | NR5A1 (0.57) | CHRNA7CHRNA10CHRNA9 | |
| SCHEMBL11828325 | 0.83 | NR5A1 (0.57) | CHRNA7CHRNA10CHRNA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7498460-B2 | Isophthalic acid derivatives | BAYER HEALTHCARE AG (DE) | 2009-03-03 | — | — | US | disclosed |
| US-7498460-B2 | Isophthalic acid derivatives | BAYER HEALTHCARE AG (DE) | 2009-03-03 | — | — | US | disclosed |
| US-7498460-B2 | Isophthalic acid derivatives | BAYER HEALTHCARE AG (DE) | 2009-03-03 | — | — | US | disclosed |
| EP-1572628-B1 | ISOPHTALIC ACID DERIVATIVES | BAYER HEALTHCARE AG (DE) | 2007-07-25 | — | — | EP | disclosed |
| EP-1572628-B1 | ISOPHTALIC ACID DERIVATIVES | BAYER HEALTHCARE AG (DE) | 2007-07-25 | — | — | EP | disclosed |
| US-20060154912-A1 | Isophtalic acid derivatives | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2006-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060154912-A1 | Isophtalic acid derivatives | VHL, FABP3, CPT1A | PPARA 42/4885KCNA3 3486/4885CHRNA7 3732/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.