Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 7/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | STS | P08842 | 4/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.45 |
| ▸ | THRA | P10827 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16516266 | 1.00 | HSD17B3 (0.57) | HSD17B3MEN1ALDH1A1MAPTHTT | |
| SCHEMBL16515826 | 1.00 | HSD17B3 (0.57) | HSD17B3MEN1ALDH1A1MAPTHTT | |
| SCHEMBL10686844 | 1.00 | HSD17B3 (0.57) | HSD17B3MEN1ALDH1A1MAPTHTT | |
| SCHEMBL8506922 | 1.00 | HSD17B3 (0.57) | HSD17B3MEN1ALDH1A1MAPTHTT | |
| SCHEMBL10683502 | 1.00 | HSD17B3 (0.57) | HSD17B3MEN1ALDH1A1MAPTHTT | |
| SCHEMBL16507742 | 1.00 | HSD17B3 (0.57) | HSD17B3MEN1ALDH1A1MAPTHTT | |
| SCHEMBL6832946 | 0.98 | HSD17B3 (0.56) | HSD17B3MEN1ALDH1A1MAPTHTT | |
| SCHEMBL27911645 | 0.93 | HSD17B3 (0.55) | HSD17B3MAPTHTTSTSHTR7 | |
| Thiophene SCHEMBL28212540 | 0.90 | HSD17B3 (0.48) | HSD17B3MEN1ALDH1A1MAPTHTT | |
| SCHEMBL827346 | 0.85 | HSD17B3 (0.52) | HSD17B3ALDH1A1MAPTSTSHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090014920-A1 | POLYMER FILAMENTS | MASSEY UNIVERSITY (NZ) | 2009-01-15 | — | — | US | claimed |
| WO-2006001719-A1 | POLYMER FILAMENTS | MASSEY UNIVERSITY (NZ) | 2006-01-05 | — | — | WO | claimed |
| EP-0253595-A2 | Novel pyrrole monomers and polymers prepared therefrom | COOKSON GROUP plc (GB) | 1988-01-20 | — | — | EP | claimed |
| CN-116837631-A | Photo-thermal evaporation and photocatalysis synergistic difunctional honeycomb fabric material and preparation method and application thereof | 中国科学院宁波材料技术与工程研究所 | 2023-10-03 | — | — | CN | disclosed |
| US-10285978-B2 | Heterocycle analogs of CAI-1 as agonists of quorum sensing in vibrio | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2019-05-14 | — | — | US | disclosed |
| US-10285978-B2 | Heterocycle analogs of CAI-1 as agonists of quorum sensing in vibrio | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2019-05-14 | — | — | US | disclosed |
| US-9968587-B2 | Heterocycle analogs of CAI-1 as agonists of quorum sensing in vibrio | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2018-05-15 | — | — | US | disclosed |
| US-9968587-B2 | Heterocycle analogs of CAI-1 as agonists of quorum sensing in vibrio | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2018-05-15 | — | — | US | disclosed |
| US-9968587-B2 | Heterocycle analogs of CAI-1 as agonists of quorum sensing in vibrio | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2018-05-15 | — | — | US | disclosed |
| US-20180078526-A1 | HETEROCYCLE ANALOGS OF CAI-1 AS AGONISTS OF QUORUM SENSING IN VIBRIO | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2018-03-22 | — | — | US | disclosed |
| US-20180078526-A1 | HETEROCYCLE ANALOGS OF CAI-1 AS AGONISTS OF QUORUM SENSING IN VIBRIO | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2018-03-22 | — | — | US | disclosed |
| US-20160200678-A1 | HETEROCYCLE ANALOGS OF CAI-1 AS AGONISTS OF QUORUM SENSING IN VIBRIO | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2016-07-14 | — | — | US | disclosed |
| WO-2015026796-A1 | HETEROCYCLE ANALOGS OF CAI-1 AS AGONISTS OF QUORUM SENSING IN VIBRIO | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2015-02-26 | — | — | WO | disclosed |
| WO-2015026796-A1 | HETEROCYCLE ANALOGS OF CAI-1 AS AGONISTS OF QUORUM SENSING IN VIBRIO | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2015-02-26 | — | — | WO | disclosed |
| US-20090014920-A1 | POLYMER FILAMENTS | MASSEY UNIVERSITY (NZ) | 2009-01-15 | — | — | US | disclosed |
| WO-2006001719-A1 | POLYMER FILAMENTS | MASSEY UNIVERSITY (NZ) | 2006-01-05 | — | — | WO | disclosed |
| EP-0332704-B1 | PROCESS FOR PRODUCING CONDUCTIVE POLYMER FILM | NIPPON SODA CO (JP) | 1994-12-21 | — | — | EP | disclosed |
| US-5306443-A | Dissolving monomer with metal containing oxidizing agent in sufficient solvent to prevent polymerization; removal of solvent | NIPPON SODA CO., LTD. (JP) | 1994-04-26 | — | — | US | disclosed |
| EP-0332704-A1 | PROCESS FOR PRODUCING CONDUCTIVE POLYMER FILM | NIPPON SODA CO., LTD. (JP) | 1989-09-20 | — | — | EP | disclosed |
| EP-0253595-A2 | Novel pyrrole monomers and polymers prepared therefrom | COOKSON GROUP plc (GB) | 1988-01-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180078526-A1 | HETEROCYCLE ANALOGS OF CAI-1 AS AGONISTS OF QUORUM SENSING IN VIBRIO | CACNG1, VIPR1, CAP1 | HSD17B3 4605/4885MEN1 4273/4885ALDH1A1 2444/4885 |
| US-10285978-B2 | Heterocycle analogs of CAI-1 as agonists of quorum sensing in vibrio | CACNG1, VIPR1, CAP1 | HSD17B3 4605/4885MEN1 4273/4885ALDH1A1 2444/4885 |
| US-20160200678-A1 | HETEROCYCLE ANALOGS OF CAI-1 AS AGONISTS OF QUORUM SENSING IN VIBRIO | CACNG1, VIPR1, CAP1 | HSD17B3 4605/4885MEN1 4273/4885ALDH1A1 2444/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.