Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 7/20 | 0.56 |
| ▸ | HTR7 | P34969 | 1/20 | 0.47 |
| ▸ | THRA | P10827 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | STS | P08842 | 4/20 | 0.44 |
| ▸ | HRH2 | P25021 | 2/20 | 0.43 |
| ▸ | HRH1 | P35367 | 2/20 | 0.43 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16515826 | 0.98 | HSD17B3 (0.57) | HSD17B3HTR7THRATHRBMEN1 | |
| SCHEMBL10686844 | 0.98 | HSD17B3 (0.57) | HSD17B3HTR7THRATHRBMEN1 | |
| SCHEMBL4527437 | 0.98 | HSD17B3 (0.57) | HSD17B3HTR7THRATHRBMEN1 | |
| SCHEMBL16516266 | 0.98 | HSD17B3 (0.57) | HSD17B3HTR7THRATHRBMEN1 | |
| SCHEMBL16507742 | 0.98 | HSD17B3 (0.57) | HSD17B3HTR7THRATHRBMEN1 | |
| SCHEMBL10683502 | 0.98 | HSD17B3 (0.57) | HSD17B3HTR7THRATHRBMEN1 | |
| SCHEMBL8506922 | 0.98 | HSD17B3 (0.57) | HSD17B3HTR7THRATHRBMEN1 | |
| SCHEMBL27911645 | 0.95 | HSD17B3 (0.55) | HSD17B3HTR7THRATHRBMAPT | |
| Thiophene SCHEMBL28212540 | 0.88 | HSD17B3 (0.48) | HSD17B3MEN1ALDH1A1MAPTHTT | |
| SCHEMBL827346 | 0.87 | HSD17B3 (0.52) | HSD17B3HTR7ALDH1A1MAPTSTS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108047406-B | A kind of preparation method of graphene/polypyrrole methylene third-order nonlinear optical composite material | 福州大学 | 2019-06-07 | — | — | CN | disclosed |
| US-10285978-B2 | Heterocycle analogs of CAI-1 as agonists of quorum sensing in vibrio | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2019-05-14 | — | — | US | disclosed |
| US-10285978-B2 | Heterocycle analogs of CAI-1 as agonists of quorum sensing in vibrio | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2019-05-14 | — | — | US | disclosed |
| CN-108047407-B | A kind of preparation method of carbon nano-tube/poly pyrroles methylene third-order nonlinear optical composite material | 福州大学 | 2019-04-02 | — | — | CN | disclosed |
| CN-108047407-A | A kind of preparation method of carbon nano-tube/poly pyrroles methylene third-order nonlinear optical composite material | 福州大学 | 2018-05-18 | — | — | CN | disclosed |
| US-9968587-B2 | Heterocycle analogs of CAI-1 as agonists of quorum sensing in vibrio | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2018-05-15 | — | — | US | disclosed |
| US-9968587-B2 | Heterocycle analogs of CAI-1 as agonists of quorum sensing in vibrio | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2018-05-15 | — | — | US | disclosed |
| US-9968587-B2 | Heterocycle analogs of CAI-1 as agonists of quorum sensing in vibrio | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2018-05-15 | — | — | US | disclosed |
| US-20180078526-A1 | HETEROCYCLE ANALOGS OF CAI-1 AS AGONISTS OF QUORUM SENSING IN VIBRIO | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2018-03-22 | — | — | US | disclosed |
| US-20180078526-A1 | HETEROCYCLE ANALOGS OF CAI-1 AS AGONISTS OF QUORUM SENSING IN VIBRIO | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2018-03-22 | — | — | US | disclosed |
| US-20180078526-A1 | HETEROCYCLE ANALOGS OF CAI-1 AS AGONISTS OF QUORUM SENSING IN VIBRIO | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2018-03-22 | — | — | US | disclosed |
| US-20160200678-A1 | HETEROCYCLE ANALOGS OF CAI-1 AS AGONISTS OF QUORUM SENSING IN VIBRIO | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2016-07-14 | — | — | US | disclosed |
| US-20160200678-A1 | HETEROCYCLE ANALOGS OF CAI-1 AS AGONISTS OF QUORUM SENSING IN VIBRIO | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2016-07-14 | — | — | US | disclosed |
| US-20160200678-A1 | HETEROCYCLE ANALOGS OF CAI-1 AS AGONISTS OF QUORUM SENSING IN VIBRIO | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2016-07-14 | — | — | US | disclosed |
| WO-2015026796-A1 | HETEROCYCLE ANALOGS OF CAI-1 AS AGONISTS OF QUORUM SENSING IN VIBRIO | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2015-02-26 | — | — | WO | disclosed |
| WO-2015026796-A1 | HETEROCYCLE ANALOGS OF CAI-1 AS AGONISTS OF QUORUM SENSING IN VIBRIO | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2015-02-26 | — | — | WO | disclosed |
| EP-1419266-A1 | DETECTION OF BACTERIAL VAGINOSIS | Osmetech PLC (GB) | 2004-05-19 | — | — | EP | disclosed |
| WO-2003016554-A1 | DETECTION OF BACTERIAL VAGINOSIS | OSMETECH PLC (GB) | 2003-02-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180078526-A1 | HETEROCYCLE ANALOGS OF CAI-1 AS AGONISTS OF QUORUM SENSING IN VIBRIO | CACNG1, VIPR1, CAP1 | HSD17B3 4605/4885HTR7 1958/4885THRA 1059/4885 |
| US-10285978-B2 | Heterocycle analogs of CAI-1 as agonists of quorum sensing in vibrio | CACNG1, VIPR1, CAP1 | HSD17B3 4605/4885HTR7 1958/4885THRA 1059/4885 |
| US-20160200678-A1 | HETEROCYCLE ANALOGS OF CAI-1 AS AGONISTS OF QUORUM SENSING IN VIBRIO | CACNG1, VIPR1, CAP1 | HSD17B3 4605/4885HTR7 1958/4885THRA 1059/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.