SCHEMBL4528142

SCHEMBL4528142

CCC(O)C#CCCCO

nearest known ligand 0.39

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.31
HMGCR P04035 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4526343 0.86
SCHEMBL11286065 0.84 TSHR (0.40) ALDH1A1SMN1; SMN2HMGCR
SCHEMBL7872938 0.82 HMGCR (0.44) ALDH1A1SMN1; SMN2HMGCR
SCHEMBL10912609 0.80 HMGCR (0.46) ALDH1A1SMN1; SMN2HMGCR
SCHEMBL31682154 0.80 HMGCR (0.46) ALDH1A1SMN1; SMN2HMGCR
SCHEMBL4530368 0.78
SCHEMBL4518639 0.76
SCHEMBL11491307 0.76 ALDH1A1 (0.31) ALDH1A1
SCHEMBL4534677 0.75
SCHEMBL6137606 0.75 HMGCR (0.46) ALDH1A1SMN1; SMN2HMGCR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7619125-B2 Hydrogenation promoter, hydrogenation catalyst, and process for producing alkene compound KANTO KAGAKU KABUSHIKI KAISHA (JP) 2009-11-17 US disclosed
US-20080033221-A1 Hydrogenation Promoter, Hydrogenation Catalyst, and Process for Producing Alkene Compound NAGOYA INDUSTRIAL SCIENCE RESEARCH INSTITUTE (JP) 2008-02-07 US disclosed