Hydrogen Sulfide

Hydrogen Sulfide

SCHEMBL4528448

CCCCCOP(=O)(O)O.S

nearest known ligand 0.91

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Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LPAR3 Q9UBY5 14/20 0.91
LPAR2 Q9HBW0 10/20 0.91
LPAR1 Q92633 7/20 0.91
LPAR5 Q9H1C0 1/20 0.55
CYP3A4 P08684 1/20 0.52
LMNA P02545 1/20 0.48
ESR1 P03372 1/20 0.48
ADORA3 P0DMS8 1/20 0.48
CDC25A P30304 1/20 0.48
AGTR1 P30556 1/20 0.48
AKT1 P31749 1/20 0.48
ADRA1A P35348 1/20 0.48
KCNH2 Q12809 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1582974 0.98 LPAR3 (0.95) LPAR3LPAR2LPAR1LPAR5CYP3A4
SCHEMBL56778 0.98 LPAR3 (0.95) LPAR3LPAR2LPAR1LPAR5CYP3A4
SCHEMBL1923668 0.95 LPAR3 (1.00) LPAR3LPAR2LPAR1LPAR5CYP3A4
Phosphoric Acid Monododecyl Ester SCHEMBL11052336 0.95 LPAR3 (1.00) LPAR3LPAR2LPAR1LPAR5CYP3A4
Phosphoric Acid Monododecyl Ester SCHEMBL9316956 0.95 LPAR3 (1.00) LPAR3LPAR2LPAR1LPAR5CYP3A4
Ammonia Solution, Strong SCHEMBL8519550 0.95 LPAR3 (0.91) LPAR3LPAR2LPAR1LPAR5CYP3A4
SCHEMBL8033780 0.95 LPAR3 (1.00) LPAR3LPAR2LPAR1LPAR5CYP3A4
Phosphoric Acid Monododecyl Ester SCHEMBL9437045 0.95 LPAR3 (1.00) LPAR3LPAR2LPAR1LPAR5CYP3A4
SCHEMBL22325599 0.95 LPAR3 (1.00) LPAR3LPAR2LPAR1LPAR5CYP3A4
SCHEMBL118839 0.95 LPAR3 (1.00) LPAR3LPAR2LPAR1LPAR5CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7599134-B2 Vision system GENTEX CORPORATION (US) 2009-10-06 US disclosed
US-20090040629-A1 Vision System BECHTEL JON H 2009-02-12 US disclosed
EP-2005233-A2 IMPROVED VISION SYSTEM Gentex Corporation (US) 2008-12-24 EP disclosed
US-7423821-B2 Vision system GENTEX CORPORATION (US) 2008-09-09 US disclosed
WO-2007111984-A2 IMPROVED VISION SYSTEM GENTEX CORPORATION (US) 2007-10-04 WO disclosed
US-20070221826-A1 Vision system GENTEX CORPORATION 2007-09-27 US disclosed