Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Sulfanilamide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 14/20 | 0.68 |
| ▸ | CA9 | Q16790 | 14/20 | 0.68 |
| ▸ | CA12 | O43570 | 13/20 | 0.68 |
| ▸ | CA1 | P00915 | 12/20 | 0.68 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.68 |
| ▸ | CA6 | P23280 | 3/20 | 0.68 |
| ▸ | CA5A | P35218 | 3/20 | 0.68 |
| ▸ | CA7 | P43166 | 3/20 | 0.68 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.68 |
| ▸ | CA4 | P22748 | 2/20 | 0.68 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.68 |
| ▸ | USP2 | O75604 | 1/20 | 0.68 |
| ▸ | TSHR | P16473 | 1/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.68 |
| ▸ | AGO2 | Q9UKV8 | 1/20 | 0.68 |
| ▸ | CA3 | P07451 | 2/20 | 0.65 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.58 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfanilamide SCHEMBL27586075 | 1.00 | CA2 (0.68) | CA2CA9CA12CA1CA14 | |
| Sulfanilamide SCHEMBL28087151 | 0.98 | CA2 (0.65) | CA2CA9CA12CA1CA14 | |
| Sulfanilamide SCHEMBL27723845 | 0.96 | CA2 (0.63) | CA2CA9CA12CA1CA14 | |
| Sulfanilamide SCHEMBL27485679 | 0.90 | CA2 (0.82) | CA2CA9CA12CA1CA14 | |
| Sulfanilamide SCHEMBL27737550 | 0.90 | CA2 (0.82) | CA2CA9CA12CA1CA14 | |
| Sulfanilamide SCHEMBL8380125 | 0.87 | CA2 (0.81) | CA2CA9CA12CA1CA14 | |
| Sulfanilamide SCHEMBL27911829 | 0.87 | CA2 (0.81) | CA2CA9CA12CA1CA14 | |
| Sulfanilamide SCHEMBL8449748 | 0.87 | CA2 (0.90) | CA2CA9CA12CA1CA14 | |
| P-Toluenesulfonamide SCHEMBL5691991 | 0.85 | CA2 (0.82) | CA2CA9CA12CA1CA14 | |
| Sulfanilamide SCHEMBL27545160 | 0.85 | CA2 (0.85) | CA2CA9CA12CA1CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 356 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105524361-A | Thermoplastic vulcanized rubber composition, and preparation method and thin film thereof | CHINA PETROLEUM & CHEM CORP | 2016-04-27 | — | — | CN | claimed |
| CN-105524362-A | Preparation method for rubber-plastic composition | CHINA PETROLEUM & CHEM CORP | 2016-04-27 | — | — | CN | claimed |
| CN-105461703-A | Preparation method of brexpiprazole | SHENZHEN FONCOO PHARMACEUTICAL CO LTD | 2016-04-06 | — | — | CN | claimed |
| CN-105440661-A | Polyamide composite core pipe and production method thereof | ZHANG ZHE | 2016-03-30 | — | — | CN | claimed |
| CN-105452528-A | Electroless nickel plating solution and method | MACDERMID ACUMEN INC | 2016-03-30 | — | — | CN | claimed |
| CN-105440465-A | Plastic-rubber composition and its preparation method and film | CHINA PETROLEUM & CHEM CORP | 2016-03-30 | — | — | CN | claimed |
| CN-103890049-B | Crosslinkable compositions crosslinkable by Real Michael Addition (RMA) reaction | NUPLEX RESINS B.V. (NL) | 2016-03-09 | — | — | CN | claimed |
| CN-105392816-A | Heat resistant polyethylene terephthalate and a process for the preparation of the same | ESTER IND LTD | 2016-03-09 | — | — | CN | claimed |
| CN-105324426-A | Composition crosslinkable by real michael addition (RMA) reaction | NUPLEX RESINS BV | 2016-02-10 | — | — | CN | claimed |
| CN-105209436-A | 3-piperidone compounds and their use as neurokinin-1 (NK1) receptor antagonists | UNIV NANYANG TECH | 2015-12-30 | — | — | CN | claimed |
| CN-1552757-A | Microporous membrane, preparing method and use | 上海杰事杰新材料股份有限公司 | 2004-12-08 | — | — | CN | claimed |
| CN-1537140-A | Biodegradable breathable hot melt composition | H��B��������ɺͽ��ڹ�˾ | 2004-10-13 | — | — | CN | claimed |
| CN-1521201-A | Waterproof ventilated microporous membrane, its preparing method and use | 上海杰事杰新材料股份有限公司 | 2004-08-18 | — | — | CN | claimed |
| CN-1511032-A | Toluene sulfonamide containing anti-tumor components and methods of use | PTS���ʹ�˾ | 2004-07-07 | — | — | CN | claimed |
| CN-1502660-A | Long carbon chain nylon compositions and preparation method thereof | 上海赛璐化工股份有限公司 | 2004-06-09 | — | — | CN | claimed |
| CN-1143885-C | Pressure sensitive adhesives | 3M | 2004-03-31 | — | — | CN | claimed |
| CN-1441770-A | Modified forms of pharmaceutically active agents and uses thereof | MEDINOX INC (US) | 2003-09-10 | — | — | CN | claimed |
| CN-1115315-A | Intermediate of pyrido-benzoxazine derivative and prepn. method | CHINA MEDICINE RESEARCH AND DE (CN) | 1996-01-24 | — | — | CN | claimed |
| CN-1095085-A | Ice-soluble paraffin wax brightening agent | GONG YOULIN (CN) | 1994-11-16 | — | — | CN | claimed |
| CN-1060862-A | Be used for the especially hot melt adhesive agent material of the raster-pattern coating of wadding of fabric | KUFNER TEXTILWERKE GMBH (DE) | 1992-05-06 | — | — | CN | claimed |