SCHEMBL4528900

SCHEMBL4528900

Nc1ccc(Cc2c(N)ccc(N)c2Cc2ccc(N)cc2)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.65
ALDH1A1 P00352 1/20 0.65
TSHR P16473 1/20 0.65
TDP1 Q9NUW8 1/20 0.65
GFER P55789 1/20 0.50
LOXL2 Q9Y4K0 1/20 0.48
CYP17A1 P05093 1/20 0.45
CYP19A1 P11511 1/20 0.45
CYP11B1 P15538 1/20 0.45
CYP11B2 P19099 1/20 0.45
MAOB P27338 4/20 0.42
MAOA P21397 2/20 0.42
MEN1 O00255 2/20 0.42
MAPT P10636 2/20 0.42
KMT2A Q03164 2/20 0.42
HRH3 Q9Y5N1 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2987811 0.85 CYP3A4 (0.48) CYP3A4ALDH1A1TSHRTDP1GFER
SCHEMBL10702190 0.85 CYP3A4 (0.59) CYP3A4ALDH1A1TSHRTDP1GFER
SCHEMBL2990081 0.84 CYP3A4 (0.52) CYP3A4ALDH1A1TSHRTDP1GFER
Hydrochloric Acid SCHEMBL2988167 0.83 CYP3A4 (0.50) CYP3A4ALDH1A1TSHRTDP1GFER
SCHEMBL6069155 0.81 CYP3A4 (0.48) CYP3A4ALDH1A1TSHRTDP1GFER
SCHEMBL10702996 0.81 CYP3A4 (0.48) CYP3A4ALDH1A1TSHRTDP1GFER
4,4'-Methylenedianiline SCHEMBL28001 0.80 CYP3A4 (1.00) CYP3A4ALDH1A1TSHRTDP1GFER
SCHEMBL6362775 0.80 CYP3A4 (1.00) CYP3A4ALDH1A1TSHRTDP1GFER
SCHEMBL8094139 0.80 CYP3A4 (1.00) CYP3A4ALDH1A1TSHRTDP1GFER
SCHEMBL3482770 0.80 CYP3A4 (1.00) CYP3A4ALDH1A1TSHRTDP1GFER

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7582691-B2 Poly(arylene ether) compositions and articles SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2009-09-01 US disclosed
US-20080171817-A1 POLY(ARYLENE ETHER) COMPOSITIONS AND ARTICLES SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2008-07-17 US disclosed