SCHEMBL4529476

SCHEMBL4529476

O=P(O)(O)CCCCCCCCCCCBr

nearest known ligand 0.58

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TYMS P04818 1/20 0.58
LPAR3 Q9UBY5 3/20 0.56
LPAR2 Q9HBW0 1/20 0.56
LMNA P02545 1/20 0.48
CYP3A4 P08684 1/20 0.48
NFKB1 P19838 1/20 0.48
BLM P54132 1/20 0.48
PMP22 Q01453 1/20 0.48
BBOX1 O75936 2/20 0.42
S1PR2 O95136 6/20 0.40
S1PR1 P21453 6/20 0.40
S1PR3 Q99500 6/20 0.40
S1PR4 O95977 5/20 0.40
S1PR5 Q9H228 2/20 0.40
ALDH1A1 P00352 3/20 0.39
TDP1 Q9NUW8 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4517898 1.00 TYMS (0.58) TYMSLPAR3LPAR2LMNACYP3A4
SCHEMBL2817555 1.00 TYMS (0.58) TYMSLPAR3LPAR2LMNACYP3A4
SCHEMBL4539408 1.00 TYMS (0.58) TYMSLPAR3LPAR2LMNACYP3A4
SCHEMBL4533342 1.00 TYMS (0.58) TYMSLPAR3LPAR2LMNACYP3A4
SCHEMBL4531839 1.00 TYMS (0.58) TYMSLPAR3LPAR2LMNACYP3A4
SCHEMBL4526564 1.00 TYMS (0.58) TYMSLPAR3LPAR2LMNACYP3A4
SCHEMBL4527382 1.00 TYMS (0.58) TYMSLPAR3LPAR2LMNACYP3A4
SCHEMBL4522106 1.00 TYMS (0.58) TYMSLPAR3LPAR2LMNACYP3A4
SCHEMBL4534184 1.00 TYMS (0.58) TYMSLPAR3LPAR2LMNACYP3A4
SCHEMBL4528496 1.00 TYMS (0.58) TYMSLPAR3LPAR2LMNACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12046269-B2 Two bit memory device and method for operating the two-bit memory device and electronic component MERCK PATENT GMBH (DE) 2024-07-23 US disclosed
US-20230010658-A1 ELECTRONIC SWITCHING DEVICE MERCK PATENT GMBH (DE) 2023-01-12 US disclosed
US-20220383924-A1 TWO BIT MEMORY DEVICE AND METHOD FOR OPERATING THE TWO-BIT MEMORY DEVICE AND ELECTRONIC COMPONENT MERCK PATENT GMBH (DE) 2022-12-01 US disclosed
WO-2021078699-A1 ELECTRONIC SWITCHING DEVICE MERCK PATENT GMBH (DE) 2021-04-29 WO disclosed
WO-2021078714-A1 TWO BIT MEMORY DEVICE AND METHOD FOR OPERATING THE TWO-BIT MEMORY DEVICE AND ELECTRONIC COMPONENT MERCK PATENT GMBH (DE) 2021-04-29 WO disclosed
EP-3813135-A1 TWO BIT MEMORY DEVICE AND METHOD FOR OPERATING THE TWO-BIT MEMORY DEVICE AND ELECTRONIC COMPONENT Merck Patent GmbH (DE) 2021-04-28 EP disclosed
EP-3813132-A1 ELECTRONIC SWITCHING DEVICE Merck Patent GmbH (DE) 2021-04-28 EP disclosed
US-20090123516-A1 DRUG DELIVERY FROM IMPLANTS USING SELF-ASSEMBLED MONOLAYERS-THERAPEUTIC SAMS THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM 2009-05-14 US disclosed
WO-2007019478-A2 DRUG DELIVERY FROM IMPLANTS USING SELF-ASSEMBLED MONOLAYERS - THERAPEUTIC SAMS BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2007-02-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230010658-A1 ELECTRONIC SWITCHING DEVICE L1CAM, GRIN2B, NBAS TYMS 3146/4885LPAR3 3888/4885LPAR2 3291/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.